Loyola Chicago at Illinois Odds, Picks and Prediction

Previewing Sunday’s No. 8 seed Loyola Chicago vs. No. 1 seed Illinois March Madness matchup, with odds and betting picks

The No. 17 Loyola Chicago Ramblers (24-4) will look to build on a seven-game winning streak when they visit the No. 2 Illinois Fighting Illini (23-6) this Sunday, March 21, 2021 at 12:10 PM ET as 6.5-point underdogs. The Fighting Illini have won eight games in a row. The point total is 133.5 for the matchup. Below, we analyze the Loyola Chicago-Illinois match up with college basketball betting odds and lines, picks and predictions.

On Friday, the Fighting Illini faced Drexel and emerged victorious, 78-49. The Fighting Illini were favored by 22.5 points and covered the spread while the teams combined to go under the 143 point total.

Lucas Williamson led the way for the Ramblers with a team-high 21 points last time out as they picked up a 71-60 win over Georgia Tech and covered the 6-point spread as favorites. The teams combined to hit the over on the 124.5 point total set for the matchup.

Loyola Chicago at Illinois: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list.
Lines last updated at 3:55 AM ET on March 20, 2021.

  • Money line: Loyola Chicago +240 (bet $100 to win $240) | Illinois -300 (bet $300 to win $100)
  • Against the spread/ATS: Loyola Chicago +6.5 (-110) | Illinois -6.5 (-110)
  • Over/Under: 133.5 (O: -110 | U: -110)

Illinois: Three things to know

  • Ayo Dosunmu leads the Fighting Illini in scoring (20.6 points per game) and assisting (5.4 assists per game). Trent Frazier is the top three-point shooter for the team, hitting 1.8 per game.
  • The 81.3 points per game the Fighting Illini put up are 25.6 more points than the Ramblers allow (55.7).
  • When Illinois scores more than 55.7 points, it is 24-6 overall and 19-0-1 against the spread.

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Loyola Chicago: Three things to know

  • Cameron Krutwig leads the Ramblers in points and rebounds. He puts up 14.9 points per game while also adding 6.7 rebounds.
  • The Ramblers put up an average of 71.5 points per game, just 2.9 more points than the 68.6 the Fighting Illini give up.
  • Loyola Chicago has put together a 14-0 ATS record and a 17-2 overall record in games where it scores more than 68.6 points.

Loyola Chicago at Illinois: Odds, betting lines, predictions and picks

Prediction

Illinois 74, Loyola Chicago 64

Money line

BetMGM and the model both have the Illinois Fighting Illini as the favorite in this game.

Against the spread (ATS)

The MGM line for this game has the Fighting Illini favored by 6.5, while the model predicts they’ll win by slightly more (9.3 points).

Over/Under (O/U)

The MGM point total for this game is just 4.7 points lower than the model projection.

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