The Los Angeles Rams (3-1) and Seattle Seahawks (2-2) kick off Week 5 with Thursday Night Football when they square off at Lumen Field in Seattle. This NFC West showdown is set for 8:20 p.m. ET. Below, we look at the Rams vs. Seahawks odds and lines, and make our best NFL picks, predictions and bets.
The Rams were just blown out 37-20 by the Arizona Cardinals Sunday. The game wasn’t even as close as the score indicates, either, as it was completely lopsided in favor of the Cardinals. The Rams are still sixth in scoring, however, and have QB Matthew Stafford playing at a high level in his first season with the team.
The Seahawks snapped their two-game losing skid with a win over the San Francisco 49ers in Week 4, largely thanks to QB Russell Wilson‘s three total touchdowns. Seattle has allowed the most yards in the NFL through four weeks, so it has been a struggle on that side of the ball.
Also see: All Week 5 odds and lines
Rams at Seahawks odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 9:05 a.m. ET.
- Money line: Rams -135 (bet $135 to win $100) | Seahawks +110 (bet $100 to win $110)
- Against the spread (ATS): Rams -2.5 (-110) | Seahawks +2.5 (-110)
- Over/Under (O/U): 54.5 (O: -112 | U: -108)
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Rams at Seahawks key injuries
Rams
- None
Seahawks
- WR Dee Eskridge (concussion) out
- LB Benson Mayowa (neck) questionable
- RB Chris Carson (neck) questionable
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Rams at Seahawks odds, lines, predictions and picks
Prediction
Rams 27, Seahawks 24
Money line
The Rams are 15-5 after a loss in Sean McVay’s tenure as head coach. They’ve dropped back-to-back games only five times in the last four years, and I don’t expect that number to grow this week.
They have a better offense and defense than Seattle, and the Seahawks’ struggles against the run will allow the Rams to control the clock and be more balanced on offense.
Bet the RAMS (-135) to win outright on the road.
Also see: Bet Slippin’ Podcast
Against the spread
The Rams are 2-2 against the spread, as are the Seahawks. The Rams are 6-3 straight up in their last nine games against Seattle, including January’s NFC Wild Card win on the road.
Playing in Seattle will be tougher this season with fans in the stands, but the Rams should probably be bigger favorites than the 2.5 points they’re giving – even on the road. I like the RAMS -2.5 (-110) to win by at least 3 points.
Over/Under
Despite Seattle’s struggles on defense and the explosiveness of its offense, the total has only gone Over in only one of four games thus far. The Rams, on the other hand, have pushed the total Over in each of their four games.
The Over is only 1-2 in the last three meetings between these teams and after the Rams failed to stop Cardinals QB Kyler Murray, they will bounce back by keeping Wilson in check. Bet the UNDER 54.5 (-108).
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