Los Angeles Rams at Arizona Cardinals odds, picks and prediction

Analyzing Monday Night Football’s Los Angeles Rams at Arizona Cardinals odds and lines, with expert NFL picks, predictions and best bets.

The Los Angeles Rams (8-4) hope to close their deficit in the NFC West standings when they visit the first-place Arizona Cardinals in the Week 14 Monday Night Football game. Kickoff is scheduled for 8:15 p.m. ET at State Farm Stadium. Below, we look at the Rams vs. Cardinals odds and lines, and make our best NFL picks, predictions and bets.

The Rams snapped a three-game losing streak in Week 13 with a 37-7 win over the Jacksonville Jaguars. They trail the Cardinals in the NFC West by two games and a loss would effectively eliminate them from contention in the division. They are No. 5 in the league in scoring, but in their three-game skid, they averaged only 18.0 points per game.

The Cardinals can clinch a postseason berth with a win Monday. In QB Kyler Murray’s return from missing three games with an ankle sprain, he threw 2 touchdowns and rushed for a pair in a 33-22 Week 13 road win over the Chicago Bears. The Cardinals beat the Rams 37-20 in Week 4 in Los Angeles.

See also: NFL Week 14 picks

Rams at Cardinals odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Sunday at 9:46 p.m. ET.

  • Money line: Rams +110 (bet $100 to win $110) | Cardinals -135 (bet $135 to win $100)
  • Against the spread (ATS): Rams +2.5 (-108) | Cardinals -2.5 (-112)
  • Over/Under (O/U): 51.5 (O: -105 | U: -115)

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Rams at Cardinals key injuries

Rams

  • OL Brian Allen (knee) doubtful
  • CB Dont’e Deayon (illness) out
  • OL Rob Havenstein (reserve/COVID-19 list) out
  • RB Darrell Henderson Jr. (reserve/COVID-19 list) out
  • LB Terrell Lewis (back) questionable

Cardinals

  • DL Zach Kerr (ribs) out
  • OL Justin Pugh (calf) questionable

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Rams at Cardinals odds, lines, predictions and picks

Prediction

Cardinals 31, Rams 23

Money line

The Cardinals beat the Rams on the road in Week 4. They have won three of their last four games. The Cards are undefeated (4-0) in division games (4-0) and they are healthy.

The Rams have lost three of their last four games, all against playoff-contending teams. They are shorthanded with their starting running back and right tackle on the reserve/COVID-19 list and CB Deayon out with an illness. Plus, starting offensive lineman Allen is doubtful.

Take the CARDINALS (-135).

Against the spread

The Cardinals are 9-3 ATS on the season. The Rams are 5-7 ATS and, before beating the Jaguars and covering the spread last week, they failed to cover the spread in five straight games.

This will be only the second time the Rams have been underdogs this season.

Take the CARDINALS -2.5 (-112).

Over/Under

Their Week 4 game went Over the O/U line (54) with 57 total points between them then.

The Cardinals have had three of their last four games cash Over tickets, while the Rams are 2-5-1 O/U in their last eight.

The Cardinals will keep up their offensive prowess and this game is critical for the Rams in the division race. They will not get blown out.

Take OVER 51.5 (-105).

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