Los Angeles Chargers at Tennessee Titans odds, picks and predictions

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The Los Angeles Chargers (0-1) face the Tennessee Titans (0-1) on Sunday in Week 2 at Nissan Stadium. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook’s lines around the Chargers vs. Titans odds, and make our expert NFL picks and predictions.

The Chargers lost a 36-34 shootout against the Miami Dolphins in Week 1, failing to cover as 3-point home favorites. To no one’s surprise, the Over of 50.5 hit in Los Angeles’ season opener.

The Titans covered as 3-point road underdogs in their 16-15 loss to the New Orleans Saints in Week 1 as the Under hit.

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Chargers at Titans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 8:33 a.m. ET.

Moneyline (ML): Chargers -150 (bet $150 to win $100) | Titans +125 (bet $100 to win $125)
Against the spread (ATS): Chargers 2.5 (-115) | Titans +2.5 (-105)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Chargers at Titans key injuries

Chargers

DE Joey Bosa (hamstring) questionable
RB Austin Ekeler (ankle) questionable
LB Eric Kendricks (hamstring/personal) questionable

Titans

WR Treylon Burks (personal) questionable
CB Kristian Fulton (hamstring) questionable
S Amani Hooker (concussion) questionable
WR DeAndre Hopkins (ankle) questionable
OL Dillon Radunz (knee) questionable
RB Tyjae Spears (groin) questionable

Chargers at Titans picks and predictions

Prediction

Chargers 27, Titans 17

Moneyline

While their defense was torched by QB Tua Tagovailoa and the Dolphins in Week 1, I’ll take the CHARGERS (-150) in Sunday’s road matchup. The Titans are a pass-funneling defense, which should allow QB Justin Herbert to thrive through the air in Week 2.

I would feel comfortable taking the moneyline in favor of Los Angeles up to -160 odds.

Against the spread

CHARGERS -2.5 (-115) is how I’d bet on the spread in this game as the offense of the Titans looked out of sorts to begin the season. Even if Ekeler is ruled out for Sunday’s contest, RB Joshua Kelley looked good with an increased role in Week 1.

Over/Under

Given Tennessee’s issues to score and there being a chance that Hopkins is sidelined, UNDER 46.5 (-110) is the play in this game. The Chargers are capable of putting up plenty of points in this bout, but the Titans could have another low-scoring offense with QB Ryan Tannehill operating the offense.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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