Los Angeles Angels at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Los Angeles Angels at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Los Angeles Angels (61-81) and Cleveland Guardians (75-65) meet Wednesday to close out a 3-game series at Progressive Field. First pitch is slated for 1:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Angels vs. Guardians odds with MLB picks and predictions.

Season series: Angels lead 4-2

Los Angeles had a 4-game win streak against Cleveland snapped with a 5-4 loss in Monday’s opener. The Angels then dropped Tuesday’s game 3-1. They are 1-5 in their last 6 games and are just 4-10 over their last 14 road games.

The Guardians have won 5 consecutive games and 7 of their last 8. That surge comes on the heels of Cleveland losing 5 in a row from Aug. 31-Sept. 4.

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Angels at Guardians projected starters

LHP Patrick Sandoval vs. RHP Cal Quantrill

Sandoval (5-9, 2.98 ERA) has authored a 1.35 WHIP, 3.8 BB/9 and 9.3 K/9 through 127 IP across 23 starts.

  • Owns a 1.67 ERA over his last 7 starts
  • Facing a Cleveland offense swung around to the lesser side of its platoon splits (.637 OPS vs. lefty pitching, 29th MLB)
  • Owns a 2.77 ERA on the road

Quantrill (12-5, 3.50 ERA) makes his 28th start. He has a 1.22 WHIP, 2.5 BB/9 and 6.2 K/9 through 157 IP.

  • Owns a 1.80 ERA over his last 7 starts
  • Has registered a 3.34 ERA at home (3.00 last 21 IP)

Angels at Guardians odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:45 a.m. ET.

  • Money line: Angels +110 (bet $100 to win $110) | Guardian -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Angels +1.5 (-190) | Guardian -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Angels at Guardians picks and predictions

Prediction

Angels 5, Guardians 4

Money line

Peg Cleveland as being buoyed by a fortunate 24-16 mark in 1-run games. Los Angeles has been hurt by its 1-run mark of 14-25.

The lefty Sandoval cuts into a Guardians blind spot, and the Cleveland bullpen is in need of a day off.

BACK LOS ANGELES (+110).

Run line/Against the spread

The extra juice here drowns out any potential on a Los Angeles lean. PASS.

Over/Under

Fading both starters and noting a fatigued Cleveland bullpen. The Angels own a .788 OPS over their last 8 road games.

TAKE THE OVER 7.5 (-130).

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