The Kansas City Chiefs (7-2) head to SoFi Stadium in Week 11 to take on the Los Angeles Chargers (5-4) Sunday at 8:20 p.m. ET (NBC). Below, we analyze Tipico Sportsbook‘s lines around the Chiefs vs. Chargers odds, and make our expert NFL picks and predictions.
The last time these AFC West rivals faced off was Week 2 when the Chiefs won 27-24, but failed to cover as 4-point favorites. The Chiefs are 6-2 against the Chargers with QB Patrick Mahomes as the starter, while the Chargers are 2-3 against Kansas City with Justin Herbert at QB (though Chad Henne started for the Chiefs in 1 of those Herbert victories).
The Chiefs have won 3 straight, their most recent against the Jacksonville Jaguars 27-17. WR Kadarius Toney had 90 yards from scrimmage and a receiving TD and his performance could be enough to earn him more looks against the Chargers, especially with Chiefs WR Mecole Hardman hitting injured reserve and WR JuJu Smith-Schuster sitting out with a concussion.
The Chargers are coming off a 22-16 loss to the San Francisco 49ers. However, L.A. could be getting a major boost on offense with injured WRs Mike Williams and Keenan Allen returning to practice this week.
FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+
Chiefs at Chargers odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:50 a.m. ET.
- Moneyline (ML): Chiefs -230 (bet $230 to win $100) | Chargers +195 (bet $100 to win $195)
- Against the spread (ATS): Chiefs -5.5 (-110) | Chargers +5.5 (-110)
- Over/Under (O/U): 52.5 (O: -111 | U: -109)
Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!
Chiefs at Chargers key injuries
Chiefs
- WR JuJu Smith-Schuster (concussion) out
Chargers
- WR Keenan Allen (hamstring) questionable
- K Dustin Hopkins (hamstring) doubtful
- WR Mike Williams (ankle) questionable
Play our free daily Pick’em Challenge and win! Play now!
Chiefs at Chargers picks and predictions
Prediction
Chiefs 33, Chargers 27
Moneyline
This game should be a thriller, as it usually is between these division rivals. The last 4 games between the Chiefs and Chargers that involved Mahomes were determined by 6 points or fewer. With Allen and Williams returning for Los Angeles, don’t expect this game to be much different.
The Chiefs’ offense is really hitting its stride and might be able to replace Smith-Schuster’s production with Toney, who is slowly finding a role on offense. Kansas City’s running game is starting to develop as well, and the Chargers are allowing the NFL’s 3rd-most rushing yards per game (146.8). With that and Chargers LB Joey Bosa still missing, the Chiefs should be able to win a shootout.
Take CHIEFS -230, but only in a parlay since the payout by itself is not great.
Against the spread
If the line was any larger than 5.5 points I’d advise against the Chiefs since they’re 3-5-1 ATS this season. But going back to that 6-point stat, I think the Chiefs can win by a touchdown.
Lean CHIEFS -5.5 (-110).
Over/Under
The last matchup between K.C. and L.A. went Under by just 1 point. This game should be different with the Chargers missing several defensive starters and the Chiefs offense playing much more like a cohesive unit.
OVER 52.5 (-111) is my favorite play for this matchup.
Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!
If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.
Follow Wesley Roesch on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Access more NFL coverage:
BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire
[lawrence-newsletter]
[lawrence-auto-related count=3 category=1367]