Jacksonville Jaguars at Los Angeles Chargers odds, picks and predictions

Analyzing Sunday’s Jacksonville Jaguars at Los Angeles Chargers odds and lines, with expert NFL picks, predictions and best bets.

The Jacksonville Jaguars (1-1) travel cross country to Sofi Stadium to take on the Los Angeles Chargers (1-1) Sunday at 4:05 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Jaguars vs. Chargers odds, and make our expert NFL picks and predictions.

The Jaguars come in after shutting out the undermanned Indianapolis Colts 24-0 Sunday. QB Trevor Lawrence had his best game as a pro and was able to find new WR Christian Kirk for 2 TDs during the blowout.

The Chargers lost 27-24 in a tough battle against the Kansas City Chiefs on Thursday Night Football in Week 2. Not just tough because it was a division game, but tough because star QB Justin Herbert was injured (ribs) in the process.

Herbert’s mobility will likely be limited if he’s able to go and that will make the return of WR Keenan Allen to the lineup even more important to coach Brandon Staley and his chances to win this game.

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Jaguars at Chargers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 6:45 a.m. ET.

  • Money line (ML): Jaguars +260 (bet $100 to win $260) | Chargers -320 (bet $320 to win $100)
  • Against the spread (ATS): Jaguars +6.5 (+102) | Chargers -6.5 (-125)
  • Over/Under (O/U): 47.5 (O: -105 | U: -115)

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Jaguars at Chargers key injuries

Jaguars

  • None

Chargers

  • WR Keenan Allen (hamstring) questionable
  • CB J.C. Jackson (ankle) questionable
  • QB Justin Herbert (ribs) questionable
  • C Corey Linsley (knee) questionable
  • TE Donald Parham Jr. (hamstring) questionable
  • OL Trey Pipkins III (ankle) questionable

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Jaguars at Chargers picks and predictions

Prediction

Chargers 31, Jaguars 20

Money line

PASS.

The Chargers may be the right side here but the line is too high to wager.

Against the spread

The Play here is CHARGERS -6.5 (-125).

The book is begging you to take this number by keeping it under 7, and I’ll bite.

I think Herbert will be playing and this line will go higher if he does, so take it now. Conversely, if you like the Jaguars, you might want to make a play now because if Herbert is ruled out, this number could drop to -2 or -3. However, I like the Chargers with or without Herbert.

Over/Under

BET the OVER 47.5 (-105).

This game will easily go Over if Herbert is playing and Allen is back. The Chargers offense has firepower even without them, with WRs Mike Williams and Josh Palmer, and RB Austin Ekeler.

Jacksonville is coming off 2 games in which it scored more than 20 points. If the Jags can get to 20 again here, this game is sure to be over the total. This is my favorite play of the game.

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