Indianapolis Colts at Houston Texans odds, picks and prediction

Analyzing Sunday’s Indianapolis Colts at Houston Texans odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (6-6) will take on the Houston Texans (2-9) at NRG Stadium Sunday in Week 13. Kickoff is set for 1 p.m. ET. Below, we look at the Colts vs. Texans odds and lines, and make our best NFL picks, predictions and bets.

The Colts absolutely destroyed the QB Davis Mills-led Texans earlier in the season. RB Jonathan Taylor went for 145 yards on 14 carries while Davis Mills threw 2 interceptions.

The Texans should begin to look like a more competent side now with QB Tyrod Taylor healthy, although they did lose to the New York Jets in Week 12.

The Texans come into this game 5-6 against the spread (ATS) while the Colts are 7-5 ATS. Indianapolis is 3-2 straight up on the road while Houston is just 1-4 at home.

Colts at Texans odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10 p.m. ET.

  • Money line: Colts -500 (bet $500 to win $100) | Texans +360 (bet $100 to win $360)
  • Against the spread (ATS): Colts -9.5 (-115) | Texans +9.5 (-105)
  • Over/Under (O/U): 44.5 (O: -105 | U: -115)

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Colts at Texans key injuries

Colts

  • DT DeForest Buckner (knee) questionable
  • TE Jack Doyle (knee) questionable
  • Andrew Sendejo (calf) questionable

Texans

  • WR Brandin Cooks (illness) questionable
  • DB Terrence Brooks (hamstring) out
  • RB David Johnson (illness, thigh) questionable
  • OL Justin McCray (concussion) out
  • DL DeMarcus Walker (hamstring) out
  • DL Jonathan Greenard (foot) questionable
  • DL Roy Lopez (illness) questionable

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Colts at Texans odds, lines, predictions and picks

Prediction

Colts 31, Texans 14

Money line

PASS on the money line.

This is a do-or-die scenario for the Colts — they must get the win, and I expect them to play like it. However, -500 odds still aren’t worth any wager, and neither is really the +360 on the Texans.

Against the spread

BET on the COLTS -9.5 (-115) despite the high spread. The Texans are coming off a 7-point loss to the Jets. This could be a good buy-low spot for them, but I wouldn’t trust Houston.

They rank 31st in opponents rushing yards per game which plays into a strength of the Colts. Taylor is leading the league in rushing yards and destroyed a weak Texans defensive line in their first meeting. He should continue that dominance.

The Colts have hit 31 points in four of their last five games. Their offense has been dynamic and I think it’ll once again prove far too much for Houston to handle.

Over/Under

“LEAN” to the OVER 44.5 (-105) as the Colts have an offense that’s been on fire as of late and it’s facing one of the league’s worst defenses.

On the flip side, there should be hope that Taylor, with another week under his belt, can produce offensively. Taylor should have the weapons to march down the field provided Cooks is able to suit up.

The Texans average 14.9 points per game, so with their inept defense, all they need to do is hit that amount.

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