Indianapolis Colts at Detroit Lions odds and lines: Colts look to end preseason undefeated

Looking at the NFL odds and lines for Friday’s Indianapolis Colts at Detroit Lions preseason Week 3 matchup.

The Indianapolis Colts (2-0) travel to meet the Detroit Lions (0-2) in their preseason finale Friday. Kickoff at Ford Field is set for 7 p.m. ET. Below, we look at the Colts vs. Lions odds and lines; check back for our NFL picks and predictions.

The Colts scratched out a 12-10 road victory against the Minnesota Vikings last week, kicking a field goal in each of the four quarters. QB Jacob Eason played well, going 16-for-27 for 132 yards, while rookie QB Sam Ehlinger tossed 2 interceptions in place of the injured QB Carson Wentz.

The Lions fell behind 23-0 on the road against the Pittsburgh Steelers but their reserves outscored the home side 20-3 in the fourth quarter to grab the backdoor cover as the Over connected.

Colts at Lions: Odds, spread and lines

Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 8:45 a.m. ET.

  • Money line: Colts -180 (bet $180 to win $100) | Lions +145 (bet $100 to win $145)
  • Against the spread/ATS: Off the board (OTB)
  • Total: 32.5 Over -115 (bet $115 to win $100) | Under -105 (bet $105 to win $100)

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2021 Preseason Betting stats:

  • ATS: Colts 2-0 | Lions 1-1
  • O/U: Colts 1-1 | Lions 1-1

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The Colts are road favorites with an implied win probability of 64.29%. Their -180 money line odds can be expressed as a fraction of 5/9 or a decimal of 1.56.

The Lions’ +145 odds represent an implied win probability of 40.82%.

The Colts and Lions must combine to score 33 or more points for a bet on the Over 32.5 to cash. A total of 32 or fewer points is a win for the Under. The odds price the Over as the more likely result on the projected total.

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