Indiana at Ohio State odds, picks and predictions

Analyzing Saturday’s Indiana at Ohio State odds and lines, with college football expert picks, predictions and best bets.

[gambcom-standard rankid=”4141″ ]

The No. 5 Indiana Hoosiers (10-0, 7-0 Big Ten) and No. 2 Ohio State Buckeyes (9-1, 6-1) meet Saturday. Kickoff from Ohio Stadium is scheduled for noon ET (FOX). Let’s analyze BetMGM Sportsbook’s college football odds around the Indiana vs. Ohio State odds, and make our expert college football picks and predictions.

New coach Curt Cignetti has the Hoosiers in unchartered territory, winning their first 10 games for the best start in program history.

This will be the Buckeyes’ third top-5 battle of the season. Ranked No. 2 on Oct. 12, they lost 32-31 as 3.5-point road favorites at then-No. 3, now-No. 1 Oregon. Ranked fourth on Nov. 2, they went to then-No. 3, now-No. 4 Penn State and won 20-13, covering as 3-point favorites.

Ohio State has won 4 in a row since the loss at Oregon, covering 2 of the past 3 outings. The Under has cashed in 4 straight, and 6 of OSU’s previous 7 outings

Indiana comes in well-rested, enjoying a bye week after a 20-15 home win vs. Michigan Nov. 9, but IU didn’t cover as a 14.5-point favorite. That halted an 8-0 against the spread (ATS) run for the Hoosiers. The Under has hit in 2 of their past 3 outings, and the defense has allowed 17 or fewer points in 4 straight games.

RankingsUS LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Indiana at Ohio State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 6:16 a.m. ET.

  • Moneyline (ML): Indiana +325 (bet $100 to win $325) | Ohio State -450 (bet $450 to win $100)
  • Against the spread: Indiana +10.5 (-110) | Ohio State -10.5 (-110)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

[gambcom-standard rankid=”4132″ ]

Indiana at Ohio State picks and predictions

Prediction

Ohio State 29, Indiana 23

Moneyline

Backing Ohio State (-450) will cost 4 ½ times the potential return. That’s way too much risk for not enough reward.

Indiana (+325) has continued to defy expectations and odds this season. If anything, it is a good value for the upset and the chance to multiply up by 3.25 times your wager. If this game were at The Rock in Bloomington rather than The Shoe in Columbus, the Hoosiers would be the play.

PASS.

Against the spread

BACK INDIANA +10.5 (-110) catching double digits. It’s a little disrespectful to the Hoosiers to be underdogs by so many points, and it’s likely they rally around each other with the bulletin board material.

The books figure that Indiana hasn’t been in such a big game recently, while Ohio State has played in two titanic games this season — at Oregon and at Penn State.

The Buckeyes should get the job done, but look for the Hoosiers to make them work for it and keep this within single digits.

Play our free daily Pick’em Challenge and win! Play now!

Over/Under

UNDER 52.5 (-110) is the lean, but don’t get carried away.

The Under has cashed in 2 of the past 3 games for the Hoosiers. Indiana’s defense has been nasty, allowing just 255.5 total yards (ranking 3rd nationally), 183.3 passing yards (20th) and 72.2 rushing yards per game (1st) this season, while yielding only 13.8 points per game (7th). But, it also hasn’t faced the likes of RB Quinshon Judkins, WR Jeremiah Smith and Co.

The Ohio State defense has been nasty, too, allowing 17 or fewer points in 4 in a row, and 7 or less on 6 different occasions. The Buckeyes allow 250.8 total yards (2nd), 160.1 passing yards (6th) and 90.7 rushing yards (4th) per game, while leading the country in least points allowed at 10.3 per game.

This won’t be a track meet, but this should at least get into the 50’s.

[gambcom-standard rankid=”6305″ ]

Want to play some games of your own? Play for free at the best social casinos and enjoy lots of slots, blackjack, video poker, roulette and more. You can even earn real prizes!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
Alabama / Arkansas / Auburn / Clemson / Colorado / DukeFlorida / Florida StateGeorgia / Iowa / KentuckyLSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / WashingtonWisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1622]