Houston Texans at Tennessee Titans odds, picks and predictions

Analyzing Saturday’s Houston Texans at Tennessee Titans odds and lines, with expert NFL picks, predictions and best bets.

The Houston Texans (1-12-1) are set to face the Tennessee Titans (7-7) on Saturday in Week 16 at Nissan Stadium. Kickoff is scheduled for 2:02 p.m. ET (CBS). Below, we analyze Tipico Sportsbook’s lines around the Texans vs. Titans odds, and make our expert NFL picks and predictions.

The Texans were defeated 30-24 by the Kansas City Chiefs in overtime in Week 15, but covered as 14.5-point underdogs. Despite losing 9 straight games, Houston has played Kansas City and the Dallas Cowboys close in the last 2 weeks.

The Titans suffered a 17-14 loss to the Los Angeles Chargers in Week 15 to push as 3-point underdogs. Tennessee has lost 4 games in a row and is now only 1 game ahead of the Jacksonville Jaguars in the AFC South.

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Texans at Titans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:59 p.m. ET.

  • Moneyline (ML): Texans +145 (bet $100 to win $145) | Titans -170 (bet $170 to win $100)
  • Against the spread (ATS): Texans +3 (-103) | Titans -3 (-117)
  • Over/Under (O/U): 34 (O: -110 | U: -110)

Texans at Titans key injuries

Texans

  • WR Nico Collins (foot) out
  • WR Brandin Cooks (calf) questionable
  • OL Kenyon Green (ankle) out
  • OL Justin McCray (hamstring) questionable
  • WR Chris Moore (foot) questionable
  • DB Steven Nelson (foot, knee) questionable

Titans

  • CB Tre Avery (concussion) questionable
  • OL Aaron Brewer (rib) questionable
  • WR Treylon Burks (concussion) questionable
  • OL Nate Davis (ankle) out
  • CB Kristian Fulton (groin) out
  • S Amani Hooker (knee) questionable
  • C Ben Jones (concussion) out
  • CB Terrance Mitchell (hamstring) out
  • OL Nicholas Petit-Frere (ankle) questionable
  • OL Dillon Radunz (knee) out
  • QB Ryan Tannehill (ankle) out

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Texans at Titans picks and predictions

Prediction

Titans 24, Texans 20

Moneyline

PASS.

The current odds for Tennessee (-170) to win straight up aren’t worth taking as the Titans will have rookie QB Malik Willis under center.

Against the spread

TITANS -3 (-117) is where I’m leaning in this game despite the loss of Tannehill. Tennessee still has RB Derrick Henry, who has rushed for 200-plus yards and multiple TDs in 4 straight matchups against Houston.

The Titans are 6-1 ATS in their last 7 games against a team with a losing record. The home team is also 9-4 ATS in the last 13 meetings between the Texans and the Titans.

Over/Under

Even with both of these teams not having high-flying offenses, OVER 34 (-110) is an intriguing bet in this contest. Henry could score nearly half or more than half of the points needed to hit the Over while the Texans have been more competitive in recent weeks.

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