The Houston Texans (1-5) seek to end their five-game losing streak but must do so on the road against the unbeaten Arizona Cardinals (6-0). Kickoff is Sunday afternoon at 4:25 p.m. ET at State Farm Stadium. Below, we look at the Texans vs. Cardinals odds and lines, and make our best NFL picks, predictions and bets.
The Texans have lost five straight since a season-opening 37-21 win over the Jacksonville Jaguars. QB Tyrod Taylor injured his hamstring in Week 2 and has not returned, meaning rookie QB Davis Mills has been the starter. In his four starts, the Texans are averaging 8.5 points per game.
The Cardinals continue to roll. They have scored more than 30 points in five of six games and held opponents to 20 points or fewer in five of six.
Arizona is fourth in the league in scoring and third in the league in scoring defense. They defeated the Cleveland Browns 37-20 in Week 6 without head coach Kliff Kingsbury, who was out after testing positive for COVID-19.
Texans at Cardinals odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 7:37 a.m. ET.
- Money line: Texans +900 (bet $100 to win $900) | Cardinals -2000 (bet $2,000 to win $100)
- Against the spread (ATS): Texans +18.5 (-112) | Cardinals -18.5 (-108)
- Over/Under (O/U): 47.5 (O: -110 | U: -110)
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Texans at Cardinals key injuries
Texans
- DT Jaleel Johnson (back) out
- C Justin Britt (knee) questionable
- WR Nico Collins (foot) questionable
Cardinals
- DT Rashard Lawrence (calf) out
- LB Jordan Hicks (toe, foot) questionable
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Texans at Cardinals odds, lines, predictions and picks
Prediction
Cardinals 37, Texans 13
Money line
The Cardinals have been great this season. They have won six in a row and, except for one game, most games haven’t even been close. They have blown out three playoff teams from last season.
The Texans have lost five straight and don’t look good on either side of the ball. But don’t waste your time money line. Houston won’t win and you won’t win enough money betting on the Cardinals to make it worth your while.
PASS.
Against the spread
Normally when I see a spread this large, I automatically take the underdog. However, I have to pause here. The Texans are 3-3 ATS but are bad both offensively and defensively.
And while this would normally be a trap game for a team like the Cardinals, who will turn around and play the 5-1 Green Bay Packers on Thursday in Week 8. The fact that they have two former Texans stars on their roster in DE J.J. Watt and WR DeAndre Hopkins means they won’t let the focus wane.
The Cardinals have covered the spread in their last four games and are 5-1 ATS this season.
Take the CARDINALS -18.5 (-108).
Over/Under
The Cardinals are 3-3 O/U this season, but two of the games that went Under missed the Over by one or two points. With the total under 50, it will depend on whether the Cardinals can get close to 40 points or if the Texans can get near 20.
I’m banking on another big offensive performance and the continued offensive struggles from the Texans. After all, the Cardinals are allowing the second-fewest points in the league and haven’t played an offense as inept as the Texans’
Take OVER 47.5 (-110).
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