The Houston Astros (13-10) take on the Colorado Rockies (13-10) for the third straight day but open a two-game set on the road at Coors Field. First pitch is at 8:40 p.m. ET. We analyze the Astros-Rockies betting odds and lines, with MLB picks and best bets.
Astros at Rockies: Projected starting pitchers
LHP Framber Valdez vs. RHP Ryan Castellani
Valdez: 1-2, 1.90 ERA, 24 K, 23 2/3 IP, 3 starts (one relief appearances)
- After walking only three total batters in his first three appearances of the season, he walked three in his last start in six innings.
- He has never faced the Rockies before.
Castellani: 0-0, 1.04 ERA, 10 K, 8 2/3 IP, 2 starts
- Castellani has not yet made it out of the fifth inning in his two major league starts.
- Opposing hitters are batting only .071 against Castellani.
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Astros at Rockies: Key injuries
Get the latest injury news here.
Astros
- OF Yordan Alvarez (knee) out
- OF Michael Brantley (quadriceps) out
- RF George Springer (wrist) questionable
- RP Roberto Osuna (elbow) out
Rockies
- LF David Dahl (back) questionable
- RP Carlos Esteves (hand) questionable
- RP Wade Davis (shoulder) out
Astros at Rockies: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 9:45 a.m. ET.
Prediction
Rockies 5, Astros 4
Moneyline (ML)
The Astros enter as favorites at -154 and have won six games in a row, including the last two games against the Rockies; however, they are only 3-6 on the road this season.
The Rockies (+140) have lost their last two games and are 3-7 in their last 10 games. Their fortunes should change coming back home. Take the ROCKIES (+140).
New to sports betting? A $10 bet on the Rockies to win returns a profit of $14.
Run line/Against the spread (ATS)
The Astros are the favorites at -1.5 (-115). Only the New York Yankees have covered more games this season than the Rockies, while the Astros are 10-13 ATS. Since we like the Rockies to win outright, you have to take them here as well. Go with the ROCKIES +1.5 (-106).
Over/Under (O/U)
The total is set at 12.5 runs for Wednesday’s game. Coors Field always gets high run totals, which likely has contributed to the Rockies having the fourth-lowest Over percentage in the league. Houston is 11-11-1 O/U.
With the pitching matchup of two players who have not given up many runs all season, expect a lower-scoring affair. Go with the UNDER 12.5 (-106).
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