The Razorbacks, the No. 2 seed in their region, host Notre Dame on Sunday afternoon at 4:30 p.m. The game can be seen on SEC Network+.
Anna Podojil potted her 15th goal of the season just five minutes in and the Hogs never looked back as Virginia Tech managed just one shot in the opening half. Reagan Swindall and Parker Goins added second-half goals to push the margin.
The Sweet 16 appearance is the third in school history. Arkansas made it to the round last year, but fell to eventual national champion Santa Clara.