Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 1 gameday inactives, weather and notes
KEY GAME-TIME DECISIONS
Early games: WR Ja’Marr Chase (active), QB Russell Wilson (inactive), WR DeAndre Hopkins (inactive), RB Antonio Gibson (active)
Afternoon games:
Sunday night:
Monday night:
Early games
Pittsburgh Steelers at Atlanta Falcons (1:00 p.m. ET)
Kickoff Weather: 75°F, mostly clear (retractable-roof dome)
Steelers
Inactives: WR Roman Wilson, S Jalen Elliott, QB Russell Wilson, DE Dean Lowry and OG Isaac Seumalo
Lineup notes: QB Russell Wilson (calf) will not play, so QB Justin Fields gets the start. RB Jaylen Warren (hamstring) practiced Thursday and Friday and will suit up.
Falcons
Inactives: CB Antonio Hamilton, DT Ruke Orhorhoro, RB Jase McClellan, OG Jovaughn Gwyn, DE Brandon Dorlus and WR Casey Washington
Lineup notes: TE Kyle Pitts (hamstring) had a full session Thursday and Friday and escapes an injury designation.
Arizona Cardinals at Buffalo Bills (1:00 p.m. ET)
Kickoff Weather: 57°F, partly cloudy, WSW 17 mph
Cardinals
Inactives: TE Travis Vokolek, LB Jesse Luketa, OG Jon Gaines II, WR Xavier Weaver and CB Darren Hall
Lineup notes: No injuries of fantasy relevance.
Bills
Inactives: LB Javon Solomon, LB Joe Andreessen, DE Dawuane Smoot, LB Edefuan Ulofoshio, S Cole Bishop, OT Ryan Van Demark and OG Sedrick Van Pran-Granger
Lineup notes: WR Curtis Samuel (toe) practiced fully all week and will play.
Tennessee Titans at Chicago Bears (1:00 p.m. ET)
Kickoff Weather: 68°F, cloudy, W 10 mph
Titans
Inactives: DL Ali Gaye, S Jamal Adams, TE David Martin-Robinson, TE Thomas Odukoya, OT John Ojukwu and LB Otis Reese
Lineup notes: WR DeAndre Hopkins (knee) was limited all week and deemed questionable but will play.
Bears
Inactives: OG Bill Murray, LB Noah Sewell, DE Dominique Robinson, WR Tyler Scott, RB Roschon Johnson, OT Kiran Amegadjie and DT Zacch Pickens
Lineup notes: WR Keenan Allen (heel) practiced fully Friday and will give it a go. RB Roschon Johnson is a healthy scratch.
New England Patriots at Cincinnati Bengals (1:00 p.m. ET)
Kickoff Weather: 64°F, clear
Patriots
Inactives: WR Javon Baker, OG Sidy Sow, OT Demontrey Jacobs, DL Eric Johnson, QB Joe Milton III, OG Zachary Thomas and LB Curtis Jacobs
Lineup notes: WR Kendrick Bourne (knee) remains on the PUP. RB Antonio Gibson (hip) is active after limited work Thursday and Friday. TE Hunter Henry (foot) practiced all week and is good to go.
Bengals
Inactives: OT Amarius Mims, TE Tanner McLachlan, WR Tee Higgins, DE Cedric Johnson, WR Kendric Pryor and DT Kris Jenkins
Lineup notes: WR Tee Higgins (hamstring) is inactive, though WR Ja’Marr Chase (personal, illness) will suit up despite not getting a new deal. Just how much he will play is an unknown. QB Joe Burrow (wrist) practiced all week and will play.
Houston Texans at Indianapolis Colts (1:00 p.m. ET)
Kickoff Weather: 64°F, clear (retractable-roof dome)
Texans
Inactives: LB Jamal Hill, WR John Metchie, RB Cam Akers, CB M.J. Stewart and OG Nick Broeker
Lineup notes: RB Cam Akers is a healthy scratch.
Colts
Inactives: PK Matt Gay, OL Blake Freeland, C Tanor Bortolini, WR Josh Downs, TE Will Mallory, CB Dallis Flowers and QB Sam Ehlinger
Lineup notes: WR Josh Downs (ankle) is out for Week 1. PK Spencer Shrader will handle the kicking duties with PK Matt Gay (hernia) ruled inactive.
Jacksonville Jaguars at Miami Dolphins (1:00 p.m. ET)
Kickoff Weather: 87°F, mostly clear
Jaguars
Inactives: S Daniel Thomas, OT Javon Foster, DE Jeremiah Ledbetter, DT Jordan Jefferson, DE Esezi Otomewo and OG Cole Van Lanen
Lineup notes: No injuries of fantasy relevance.
Dolphins
Inactives: DB Ethan Bonner, LB Channing Tindall, C Andrew Meyer, RB Jaylen Wright, WR Malik Washington and LB Mohamed Kamara
Lineup notes: WR Tyreek Hill (thumb) dealt with a thumb issue in the preseason, but he hasn’t been on the injury report all week. Hill was detained by police for a reported traffic violation while entering the stadium grounds, but he will play, according to his agent. CB Jalen Ramsey (hamstring) is active, as expected. RB Jaylen Wright‘s NFL debut will have to wait after a healthy scratch.
Carolina Panthers at New Orleans Saints (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Panthers
Inactives: DL LaBryan Ray, CB Shemar Bartholomew, S Jammie Robinson, OG Andrew Raym, OT Jarrett Kingston, TE Messiah Swinson and TE Tommy Tremble
Lineup notes: TE Tommy Tremble (hamstring, back) and TE Ian Thomas (calf), the team’s top-two tight ends were ruled out this week. Thomas has since been placed on IR. RB Miles Sanders (finger) had a full session Friday and is good to go.
Saints
Inactives: WR A.T. Perry, LB D’Marco Jackson, DT John Ridgeway, TE Dallin Holker, QB Spencer Rattler, DL Khalen Saunders and LB Jaylan Ford
Lineup notes: RB Kendre Miller (hamstring) is on IR and will miss the first four games.
Minnesota Vikings at New York Giants (1:00 p.m. ET)
Kickoff Weather: 64°F, mostly clear
Vikings
Inactives: DT Levi Drake Rodriguez, CB Dwight McGlothern, DB Fabian Moreau, WR Trishton Jackson, QB Brett Rypien, OT Walter Rouse and DL Jalen Redmond
Lineup notes: TE T.J. Hockenson (knee) remains on the PUP. WRs Jordan Addison (ankle) and Jalen Nailor (ankle) participated fully Friday and will go.
Giants
Inactives: CB Anthony Johnson, OG Jake Kubas, QB Tommy DeVito, S Tre Hawkins III and DE Carlos Basham Jr.
Lineup notes: No injuries of fantasy relevance.
Late afternoon
Las Vegas Raiders at Los Angeles Chargers (4:05 p.m. ET)
Kickoff Weather: 102°F, clear, SW 10 mph (open-air dome)
Raiders
Inactives: WR Ramel Keyton, C Jackson Powers-Johnson, S Thomas Harper, CB Decamerion Richardson and RB Dylan Laube
Lineup notes: TE Brock Bowers (foot) made it through a full practice Friday and is good to go. Rookie OG Jackson Powers-Johnson (illness) was ruled out for his would-be NFL debut, and RB Dylan Laube‘s rookie season also begins on the inactives list.
Chargers
Inactives: CB Tarheeb Still, QB Taylor Heinicke, WR Brenden Rice, OG Jordan McFadden, DE Justin Eboigbe and RB Kimani Vidal
Lineup notes: WR DJ Chark Jr. (hip) was placed on IR on Saturday. QB Justin Herbert (foot) and WR Joshua Palmer (knee) had minor issues Thursday and Friday, but they practiced fully both days. Rookies RB Kimani Vidal and WR Brenden Rice are both healthy scratches to begin their pro careers.
Denver Broncos at Seattle Seahawks (4:05 p.m. ET)
Kickoff Weather: 73°F, clear
Broncos
Inactives: WR Troy Franklin, DT Eyioma Uwazurike, OT Frank Crum, CB Kris Abrams-Draine, QB Zach Wilson and TE Lucas Krull
Lineup notes: No injuries of fantasy relevance.
SEahawks
Inactives: CB Artie Burns, OT Mike Jerrell, DT Myles Adams, TE Pharaoh Brown, LB Uchenna Nwosu, OT Jalen Sundell and OG Sataoa Laumea
Lineup notes: WR Tyler Lockett (thigh) is ready to go. TE Noah Fant (toe) will play as well.
Dallas Cowboys at Cleveland Browns (4:25 p.m. ET)
Kickoff Weather: 63°F, clear, W 13 mph
Cowboys
Inactives: CB Andrew Booth Jr., WR Ryan Flournoy, QB Trey Lance, TE John Stephens, OT Matt Waletzko and LB Buddy Johnson
Lineup notes: WR CeeDee Lamb was officially elevated from the exempt list and will play.
Browns
Inactives: QB Dorian Thompson-Robinson, OG Javion Cohen, OT Jedrick Wills, CB Myles Harden, DL Isaiah McGuire, OT Jack Conklin and CB Kahlef Hailassie
Lineup notes: RB Nick Chubb (knee) remains on the PUP. LT Jedrick Wills (knee) is out, and RT Jack Conklin (knee) was declared inactive, meaning both starting bookends are not on the field. WR Jerry Jeudy (knee) practiced fully all week and will roll.
Washington Commanders at Tampa Bay Buccaneers (4:25 p.m. ET)
Kickoff Weather: 77°F, 55% chance of light rain
Commanders
Inactives: QB Sam Hartman, DT Jer’Zhan Newton, S Darrick Forrest Jr., S Dominique Hampton, WR Noah Brown and OT Chris Paul
Lineup notes: No injuries of fantasy relevance.
Buccaneers
Inactives: TE Devin Culp, DE Jose Ramirez, S Kaevon Merriweather, CB Tyrek Funderburk, DL Calijah Kancey, OG Royce Newman and DE Logan Hall
Lineup notes: WR Trey Palmer (concussion) practiced all week but remains questionable.
Sunday Night Football
Los Angeles Rams at Detroit Lions (8:20 p.m. ET)
Kickoff Weather: Dome stadium
Rams
Inactives: DE Brennan Jackson, DL Desjuan Johnson, LB Elias Neal, OT Rob Havenstein and RB Cody Schrader
Lineup notes: TE Tyler Higbee (knee) remains on the PUP. RT Rob Havenstein (ankle) couldn’t get right in time. WR Puka Nacua (knee) practiced fully all week and is good to go.
Lions
Inactives: OT Colby Sorsdal, CB Ifeatu Melifonwu, DL D.J. Reader, DB Loren Strickland, DL James Houston, OT Giovanni Manu and LB Trevor Nowaske
Lineup notes: No injuries of fantasy relevance.
Monday Night Football
New York Jets at San Francisco 49ers (8:15 p.m. ET)
Kickoff Weather:78°F, clear, NNW 10 mph
Jets
Lineup notes: WR Mike Williams (knee) practiced fully all week and isn’t on the final report with a designation.
49ers
Lineup notes: RB Elijah Mitchell (hamstring) will spend the season on IR. RB Christian McCaffrey (calf, Achilles) is inactive, and RB Jordan Mason will start.