First look: Tennessee Titans at New England Patriots odds and lines

Looking at Sunday’s Tennessee Titans at New England Patriots Week 12 NFL odds, lines and trends. Here’s what you need to know.

The Tennessee Titans (8-3) meet the New England Patriots (7-4) Sunday at 1 p.m. ET for their Week 12 showdown at Gillette Stadium. Below, we look at the Titans vs. Patriots odds and lines; check back for our NFL picks and predictions.

Tennessee had its six-game winning streak snapped Sunday with a 22-13 home loss to the Houston Texans as a 10.5-point favorite. The Titans outgained the Texans 420-190 in total yards and converted 11 more first downs but were minus-5 in turnover differential.

The Titans still have a two-game lead over the Indianapolis Colts atop the AFC South.

New England beat the brakes off the Atlanta Falcons 25-0 Thursday Night Football in Week 11. The Patriots held the Falcons to just 165 total yards and 11 first downs and were plus-3 in turnover differential.

New England pulled ahead of the Buffalo Bills atop the AFC East after the Bills were upset by the Colts at home Sunday.

Titans at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Sunday at 5:50 p.m. ET.

  • Money line: Titans +135 (bet $100 to win $135) | Patriots -170 (bet $170 to win $100)
  • Against the spread (ATS): Titans +3.5, -125 (bet $125 to win $100) | Patriots -3.5, +102 (bet $100 to win $102)
  • Over/Under (O/U): 45.5, O: -115 (bet $115 to win $100) | U: -105 (bet $105 to win $100)

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2021 betting stats:

  • ML: Titans 8-3 | Patriots 7-4
  • ATS: Titans 7-4 | Patriots 7-4
  • O/U: Titans 6-5 | Patriots 5-6

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Titans at Patriots head-to-head

The Titans are 2-0 vs. the Patriots since hiring head coach Mike Vrabel in 2018, both times as underdogs.

Tennessee upset New England 34-10 in Week 10 of 2018, and 20-13 the following season in an AFC Wild Card game.

However, Titans RB Derrick Henry (sidelined since a Week 8 foot injury) was crucial in both wins and, obviously, QB Tom Brady is no longer under center for the Patriots.

New England is just 8-10 ATS when playing with a rest advantage since 2016 but 28-17-1 ATS as a home favorite. Tennessee is 11-6 ATS as a road underdog and 8-4 ATS when playing with a rest disadvantage in the Vrabel era.

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