The No. 14 Syracuse Orange (6-0, 3-0 ACC) and No. 5 Clemson Tigers (7-0, 5-0) meet Saturday at Memorial Stadium in Clemson, S.C. Kickoff is scheduled for noon ET (ABC). Below, we look at Syracuse vs. Clemson odds from Tipico Sportsbook; check back for all our college football picks and predictions.
The Orange moved to 6-0 with a 24-9 win over NC State last weekend at the JMA Wireless Dome. Syracuse is also 5-1 ATS, and the defense has allowed just 9 points in the past 2 games, while cashing the Under in 3 in a row.
The Tigers have scored 30 or more points in all 7 games this season, and Clemson’s high-octane attack will be the biggest challenge for the Syracuse defense yet. Clemson has covered each of the past 3 games, too.
Syracuse is No. 14 and Clemson is No. 5 in the AFCA Coaches Poll powered by USA TODAY Sports.
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Syracuse at Clemson odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2:15 p.m. ET.
- Moneyline (ML): Off the board.
- Against the spread (ATS): Syracuse +13.5 (-108) | Clemson -13.5 (-112)
- Over/Under (O/U): 51.5 (O: -115 | U: -107)
2022 betting stats
- ML: Syracuse 6-0 | Clemson 7-0
- ATS: Syracuse 5-1 | Clemson 4-3
- O/U: Syracuse 2-4 | Clemson 4-3
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Syracuse at Clemson head-to-head
The Tigers lead the all-time series 8-2, including victories in each of the past four matchups. Clemson eked out a 17-14 victory in Syracuse last season, while winning 47-21 in the most recent meeting at Death Valley Oct. 24, 2020.
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