First look: Ole Miss at LSU odds and lines

Looking at Saturday’s Ole Miss at LSU college football odds, lines and trends. Here’s what you need to know.

The LSU Tigers (5-2, SEC 3-1) welcome the No. 7 Ole Miss Rebels (7-0, 3-0) to Tiger Stadium Saturday. Kickoff is set for 3:30 p.m. ET (CBS). Below, we look at Ole Miss vs. LSU odds from Tipico Sportsbook; check back for all our college football picks and predictions.

LSU, the first team outside of the AFCA Coaches Poll, is coming off a 45-35 win over Florida. The week prior, it was destroyed by Tennessee 40-13. LSU also has a key win over Mississippi State this season.

The Tigers are led by coach Brian Kelly, who is in his first season in Baton Rouge, leading Notre Dame for the 12 prior. LSU’s main weapon is QB Jayden Daniels, who leads the team in both passing and rushing yards.

Ole Miss is led by QB Jaxson Dart, who is 12 yards shy of 1,500 on the season. The Rebels also have a pair of running backs that each have over 600 yards on the ground.

Ole Miss is No. 7 in the AFCA Coaches Poll powered by USA TODAY Sports. Its key win this season was a 22-19 home victory over the top-25 Kentucky Wildcats.

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Ole Miss at LSU odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 2:20 p.m. ET.

  • Moneyline (ML): Off the board.
  • Against the spread (ATS): Ole Miss +1.5 (-107) | LSU -1.5 (-115)
  • Over/Under (O/U): 66.5 (O: -108 | U: -112)

2022 betting stats

  • ML: Ole Miss 7-0 | LSU 5-2
  • ATS: Ole Miss 3-4 | LSU 4-3
  • O/U: Ole Miss 3-4 | LSU 2-5

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Ole Miss vs. LSU head-to-head

Both Ole Miss and LSU joined the SEC in its inaugural season almost a century ago, founded in 1932.

Ole Miss won at home last season, but that is as far as its success has gone. Before 2021, LSU won the previous 5 matchups. LSU also has 23 more wins in the series and an overall 64-41-4 record.

LSU has both a top-50 offense and defense of the 131 FBS programs, scoring 33.7 points per game and allowing just 21.3. Ole Miss can impressively top that with a top-16 offense and defensive, scoring 40.9 per game and allowing 17.3.

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