The No. 12 Ole Miss Rebels (3-0, 0-0 SEC) and No. 1 Alabama Crimson Tide (4-0, 1-0) meet Saturday at Bryant-Denny Stadium in Tuscaloosa, Alabama. Kickoff is scheduled for 3:30 p.m. ET. Below, we look at the Ole Miss vs. Alabama odds and lines; check back for our college football picks and predictions.
The Rebels, No. 12 in the AFCA Coaches Poll powered by USA TODAY Sports, buried Tulane last time out by a 61-21 score, and they’re now 2-0-1 ATS across three outings while ranking No. 1 in the nation in total yards per game (635.3) and points scored per game (52.7).
The No. 1 Tide posted a season-high 63 points in a win over Southern Miss Saturday, hitting the Over for the third consecutive outing. Alabama has posted 44 or more points in three of four games, and it’s averaging 46.5 PPG to rank fourth in the country.
Ole Miss at Alabama odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 10:35 a.m. ET.
- Money line: Ole Miss +470 (bet $100 to win $470) | Alabama -700 (bet $700 to win $100)
- Against the spread (ATS): Ole Miss +14.5, -112 (bet $112 to win $100) | Alabama -14.5, -108 (bet $108 to win $100)
- Over/Under (O/U): 79.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)
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2021 betting stats:
- ML: Ole Miss 3-0 | Alabama 4-0
- ATS: Ole Miss 2-0-1 | Alabama 2-2
- O/U: Ole Miss 2-1 | Alabama 3-1
Ole Miss at Alabama head-to-head
The Crimson Tide has dominated this series, leading 52-10-2 in 64 all-time meetings. Alabama won 63-48 last season on Oct. 10, 2020 in Oxford, and each of the past five in the series. The last win for Ole Miss came on Sept. 19, 2015 in Tuscaloosa, a 43-37 victory.
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