First look: Ohio State at Northwestern odds and lines

Looking at Saturday’s Ohio State at Northwestern college football odds, lines and trends. Here’s what you need to know.

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The second-ranked Ohio State Buckeyes (8-1, 5-1 Big Ten) and the Northwestern Wildcats (4-5, 2-4) meet Saturday at Wrigley Field in Chicago. Kickoff is scheduled for noon ET (FOX). Below, we look at Ohio State vs. Northwestern odds from FanDuel Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Buckeyes rolled up a 45-0 victory over the Purdue Boilermakers at The Horseshoe Saturday, covering as 37-point favorites with the Under (56) cashing. The Buckeyes defense has allowed just 30 total points in the past 3 games — vs. Nebraska, Penn State and Purdue — while the Under is 3-0 in those contests, and 5-1 in the previous 6 outings.

The Wildcats also played Purdue in their most recent game (Nov. 2), posting a 26-20 victory in overtime as 2.5-point underdogs in West Lafayette. The Over (44) cashed, thanks to the extra session. The Over has cashed 2 in a row, and in 4 of the past 5 Northwestern contests.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Ohio State at Northwestern odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Sunday at 2:43 p.m. ET.

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Ohio State -31.5 (-108) | Northwestern +31.5 (-112)
  • Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Ohio State 8-1 | Northwestern 4-5
  • ATS: Ohio State 5-4 | Northwestern 3-6
  • O/U: Ohio State 4-5 | Northwestern 5-4

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Ohio State vs. Northwestern head-to-head

Ohio State leads the all-time series 65-14-1, including wins in each of the past 10 matchups. That includes a 21-7 victory in Evanston in the most recent meeting (November 2022) in a game with terrible windy conditions.

This will be the first meeting at a neutral site since Dec. 19, 2020, in the Big Ten Championship Game when the Buckeyes posted a 22-10 win at Lucas Oil Stadium in Indianapolis.

The last Wildcats’ victory a 33-w7 win in Evanston Oct. 2, 2004. Prior to that, their last win in the series was in 1971.

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