First look: Ohio State at Michigan State odds and lines

Looking at Saturday’s Ohio State at Michigan State college football odds, lines and trends. Here’s what you need to know.

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The 3rd-ranked Ohio State Buckeyes (3-0, 0-0 Big Ten) and the Michigan State Spartans (3-1, 1-0) meet Saturday in a conference matchup at Spartan Stadium. Kickoff is scheduled for 7 p.m. ET (Peacock). Below, we look at Ohio State vs. Michigan State odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Buckeyes were back Saturday after a bye, and they rolled up a 49-14 win over Marshall as a 40-point favorite while the Over (57) cashed. Ohio State is just 1-2 against the spread (ATS) in 3 games. It has scored 49 or more points in each game, cashing high on the total in each outing.

The Spartans lost 23-19 at Boston College on Saturday night, although it hung on for a cover as a 5-point underdog. It has alternated covers and non-covers in its 4 games, and Michigan State has cashed low on the total in 3 of 4 outings.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Ohio State at Michigan State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 6:10 a.m. ET.

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Ohio State -24.5 (-110) | Michigan State +24.5 (-110)
  • Over/Under (O/U): 49.5 (O: -110 | U: -110)

FanDuel Sportsbook lists a ML of:

  • Ohio State -4500 (bet $4,500 to win $100)
  • Michigan State +1600 (bet $100 to win $1,600)

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2024 betting stats

  • ML: Ohio State 3-0 | Michigan State 3-1
  • ATS: Ohio State 1-2 | Michigan State 2-2
  • O/U: Ohio State 3-0 | Michigan State 1-3

Ohio State at Michigan State head-to-head

Ohio State leads the all-time series 37-15, while winning 8 in a row in the series. The Buckeyes have covered 7 in a row in the series, too, while the Over has cashed in the past 2 meetings in East Lansing. The Under is 7-2 in the previous 9 battles in the series, however.

The Buckeyes won 38-3 last season on Nov. 11, while posting a 49-20 win in the most recent visit to East Lansing on Oct. 8, 2022.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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