The New England Patriots (8-4) and Buffalo Bills (7-4) meet in the Week 13 Monday Night Football game at Highmark Stadium. Kickoff is slated for 8:15 p.m. ET. Below, we look at the Patriots vs. Bills odds and lines; check back for our NFL picks and predictions.
New England clobbered the Tennessee Titans 36-13 for a sixth win in a row. QB Mac Jones threw for a career-high 310 yards in the triumph at home. The Pats now hit the road where they are 5-0 this season.
The Bills throttled the New Orleans Saints 31-6 Thanksgiving night. Buffalo outgained New Orleans 361 yards to 190, and QB Josh Allen completed 23 of 28 pass attempts while tossing 4 touchdowns. The defensive performance was the fourth time the Bills held an opponent under 10 points this season.
Also see: All Week 13 odds and lines
Patriots at Bills odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 5:20 p.m. ET.
- Money line: Patriots +130 (bet $100 to win $130) | Bills -160 (bet $160 to win $100)
- Against the spread (ATS): Patriots +3.5, -130 (bet $130 to win $100) | Bills -3.5, +105 (bet $105 to win $100)
- Over/Under (O/U): 43.5, O: -115 (bet $115 to win $100) | U: -105 (bet $105 to win $100)
Also see: Betting 101
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2021 betting stats:
- ML: Patriots 8-4 | Bills 7-4
- ATS: Patriots 8-4 | Bills 6-4-1
- O/U: Patriots 6-6 | Bills 5-6
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Patriots at Bills head-to-head
Buffalo took last season’s series 2-0, winning by 3 and 29 points in the twin wins. Those victories came on the heels of a seven-game New England win streak in a series that dates back to 1960. The Patriots lead that all-time series 76-45-1.
Against the spread, the Bills have gone 3-1-1 in their last five games against the Pats. The Under is 4-2 across the last six meetings.
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