First look: Miami Dolphins at Buffalo Bills odds and lines

Looking at Saturday’s Miami Dolphins at Buffalo Bills Week 15 NFL odds, lines and trends. Here’s what you need to know.

The Miami Dolphins (8-5) face the Buffalo Bills (10-3) Saturday in Week 15. Kickoff from Highmark Stadium is set for 8:15 p.m. ET (NFL Network). Below, we look at Dolphins vs. Bills odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Dolphins fell 23-17 at the Los Angeles Chargers Sunday, losing outright as 3-point favorites. Miami has dropped 2 straight games and has lost 3 of its last 5 against the spread (ATS). QB Tua Tagovailoa was held to just 145 passing yards, and his 35.7% completion percentage (10 of 28) was his lowest of the season. The Fins will wrap up a 3-game road trip in Week 15.

Also seeAll Week 15 odds and lines

The Bills held off the New York Jets 20-12 on Sunday, capturing their 4th straight victory but failing to cover a 10-point spread. Buffalo is just 2-4 ATS in its last 6 games. QB Josh Allen was held to a season-low 147 passing yards, although he paced the team in rushing with 47 yards and a TD on 10 carries.

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Dolphins at Bills odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:27 p.m. ET.

  • Moneyline (ML): Dolphins +280 (bet $100 to win $280) | Bills -340 (bet $340 to win $100)
  • Against the spread (ATS): Dolphins +7.5 (-114) | Bills -7.5 (-106)
  • Over/Under (O/U): 42 (O: -110 | U: -110)

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2022 betting stats

  • ML: Dolphins 8-5 | Bills 10-3
  • ATS: Dolphins 6-7 | Bills 6-6-1
  • O/U: Dolphins 6-7 | Bills 3-10

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Dolphins vs. Bills head-to-head

These long-time division rivals have met 117 times since the series kicked off in 1966. Miami leads the series 62-54-1, although the Bills are 3-1 in their 4 postseason meetings.

Miami picked up a 21-19 victory in Florida in Week 3 this season, snapping Buffalo’s 7-game win streak in the series. Buffalo leads 5-4-1 ATS in the last 10 meetings and — while the Under has come through in the last 3 meetings — the O/U is 5-5 in that span.

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