The Kansas City Chiefs (9-4) and Los Angeles Chargers (8-5) meet for an AFC West showdown on Thursday Night Football. Kickoff from SoFi Stadium is set for 8:20 p.m. ET. Below, we look at the Chiefs vs. Chargers odds and lines; check back for our NFL picks and predictions.
Also see: All Week 15 odds and lines
The Chiefs scored a season-high 48 points in their defeat of the Las Vegas Raiders in Week 14. Kansas City opened the scoring just 17 seconds into the game as CB Mike Hughes converted a recovered fumble into a touchdown, the first of 5 forced turnovers for K.C.
QB Patrick Mahomes finished with 258 passing yards and 2 touchdowns, marking the first time he’s thrown a touchdown since a Week 10 meeting with these same Raiders. RB Clyde Edwards-Helaire scored twice out of the backfield and finished with 37 yards on 10 carries.
The Chargers also picked up a Week 14 victory as they toppled the New York Giants 37-21. The final score actually makes the game look much closer than it was as the Giants scored 14 unanswered points in the final 4:33 to tighten up a 37-7 Chargers lead.
QB Justin Herbert finished with 275 passing yards and 3 touchdowns, connecting with WR Jalen Guyton, WR Joshua Palmer and TE Jared Cook on the 3 scores. Running back Austin Ekeler was forced from the game with an ankle injury early in the second half and finished with 67 yards and a touchdown on 12 carries. There has been no update on his status for Thursday’s game.
Chiefs at Chargers odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 11:39 a.m. ET.
- Money line: Chiefs -190 (bet $190 to win $100) | Chargers +155 (bet $100 to win $155)
- Against the spread (ATS): Chiefs -3.5, -110 (bet $110 to win $100) | Chargers +3.5, -110 (bet $110 to win $100)
- Over/Under (O/U): 50.5, O: -115 (bet $115 to win $100) | U: -105 (bet $105 to win $100)
Also see: Betting 101
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2021 betting stats:
- ML: Chiefs 9-4 | Chargers 8-5
- ATS: Chiefs 6-7 | Chargers 7-6
- O/U: Chiefs 6-7 | Chargers 6-7
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Chiefs at Chargers head-to-head
Kansas City leads the all-time series 64-58-1 but lost the one postseason matchup.
These series between the longtime division rivals dates back to 1960 when Kansas City was the Dallas Texans and Los Angeles was … well, Los Angeles before moving to San Diego where it played from 1961 to the 2016-’17 season.
The Chiefs are 7-3 in the last 10 meetings, although the Chargers have won two in a row, including a 30-24 road victory in Week 3 of this season. Kansas also leads 5-4-1 ATS across that span, while the O/U is 5-5.
Kansas City is 4-0 ATS entering Thursday’s game but is 0-3-1 ATS in its last four against Los Angeles.
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