The Jacksonville Jaguars (2-3) travel to take on the Indianapolis Colts (2-2-1) Sunday in Week 6. Kickoff from Lucas Oil Stadium 1 p.m. ET (CBS). Below, we look at Jaguars vs. Colts odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
The Jaguars got off to a 2-1 start to the season before losing their last 2 games to the Philadelphia Eagles (29-21) and the Houston Texans (13-6). QB Trevor Lawrence has turned the ball over a combined 7 times in the last 2 weeks and will look to do a better job protecting the ball Sunday.
The Colts were able to squeak out a narrow 12-9 victory in Week 5 against the Denver Broncos in a game where both offenses were unable to get much going. Indianapolis will also need QB Matt Ryan to protect the football as he’s thrown 7 interceptions and fumbled the ball 11 times (3 lost).
Also see: All Week 6 odds and lines
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Jaguars at Colts odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 8:50 a.m. ET.
- Moneyline (ML): Jaguars +105 (bet $100 to win $105) | Colts -125 (bet $125 to win $100)
- Against the spread (ATS): Jaguars +2.5 (-112) | Colts -2.5 (-108)
- Over/Under (O/U): 41.5 (O: -105 | U: -115)
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2022 betting stats
- ML: Jaguars 2-3 | Colts 2-2-1
- ATS: Jaguars 2-3 | Colts 2-3
- O/U: Jaguars 3-2 | Colts 0-5
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Jaguars vs. Colts head-to-head
This Sunday’s showdown will be the 44th meeting between the Jaguars and the Colts. Indianapolis has a 26-17 edge in the all-time matchup.
The Jaguars have had more success recently, though, winning 4 of the last 6 games in the series. Jacksonville has won 2 straight against Indianapolis and shut out the Colts 24-0 at home in Week 2.
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