First look: Jacksonville Jaguars at Indianapolis Colts odds and lines

Looking at Sunday’s Jacksonville Jaguars at Indianapolis Colts Week 10 NFL odds, lines and trends. Here’s what you need to know.

The Jacksonville Jaguars (2-6) travel to meet the Indianapolis Colts (4-5) Sunday for a Week 10 game at Lucas Oil Stadium. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Jaguars vs. Colts odds and lines; check back for our NFL picks and predictions.

The Jaguars stunned the Buffalo Bills by a 9-6 count in a low-scoring affair that featured zero touchdowns in Week 9. Jacksonville has won and covered two of its last three games and the Under is 6-1 across its last seven.

The Colts have had a couple of extra days to rest following a 45-30 win in Week 9 on Thursday Night Football. Indianapolis has won three of its last four outings while going 5-1 ATS across the past six contests. The Over has cashed in three straight games, too.

Also see: All Week 10 odds and lines

Jaguars at Colts odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 8:51 a.m. ET.

  • Money line: Jaguars +370 (bet $100 to win $370) | Colts -520 (bet $520 to win $100)
  • Against the spread (ATS): Jaguars +9.5, +100 (bet $100 to win $100) | Colts -9.5, -120 (bet $120 to win $100)
  • Over/Under (O/U): 47.5, O: -112 (bet $112 to win $100) | U: -108 (bet $108 to win $100)

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2021 betting stats:

  • ML: Jacksonville 2-6 | Indianapolis 4-5
  • ATS: Jacksonville 3-5 | Indianapolis 6-3
  • O/U: Jacksonville 2-6 | Indianapolis 6-3

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Jaguars at Colts head-to-head

The Colts won 28-14 in the most recent meeting in Indianapolis Jan. 3, 2021, but the Jaguars covered a 15.5-point number. In fact, Jacksonville is 3-0 ATS across the past three meetings, and 8-1-1 ATS in the previous 10 meetings overall. The Over has hit in three of the previous four in the series.

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