First look: Carolina Panthers at Buffalo Bills odds and lines

Looking at Sunday’s Carolina Panthers at Buffalo Bills Week 15 NFL odds, lines and trends. Here’s what you need to know.

The Carolina Panthers (5-8) and Buffalo Bills (7-6) meet in a Week 15 game Sunday at Highmark Stadium in Orchard Park, N.Y. Below, we look at the Panthers vs. Bills odds and lines; check back for our NFL picks and predictions.

The Panthers were on the short end of a 29-21 home loss to the Atlanta Falcons, losing for the third consecutive time since winning at Arizona in Week 10. Carolina is 0-3 SU/ATS across the past three, while hitting the Over in four straight outings.

The Bills nearly pulled off a huge comeback at the Tampa Bay Buccaneers in Week 14, falling 33-27 in overtime. Buffalo has lost back-to-back games for the first time this season, and has failed to cover in consecutive games for the first time, too.

Also see: All Week 15 odds and lines

Panthers at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 3:23 a.m. ET.

  • Money line: Panthers +420 (bet $100 to win $420) | Bills -600 (bet $600 to win $100)
  • Against the spread (ATS): Panthers +10.5, -115 (bet $115 to win $100) | Bills -10.5, -105 (bet $105 to win $100)
  • Over/Under (O/U): 43.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)

Also see: Betting 101

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

2021 betting stats:

  • ML: Panthers 5-8 | Bills 7-6
  • ATS: Panthers 5-8 | Bills 6-6-1
  • O/U: Panthers 6-7 | Bills 6-7

Panthers at Bills head-to-head

The last time these teams faced each other, Carolina scratched out a 9-3 win at Bank of America Stadium Sept. 17, 2017. The last time they met in Buffalo was Sept. 15, 2013 with the Bills squeaking out a 24-23 victory.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter and SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]