First look: Buffalo Bills at New England Patriots odds and lines

Looking at Sunday’s Buffalo Bills at New England Patriots odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (13-3) and New England Patriots (3-13) meet Sunday in Week 18. Kickoff from Gillette Stadium is scheduled for 1 p.m. ET (CBS). Below, we look at Bills vs. Patriots odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Bills locked up the No. 2 seed in the AFC with a commanding 40-14 win over the New York Jets on Sunday, covering as 10.5-point road favorites as the Over 44 hit with ease. QB Josh Allen shined again, delivering 3 TDs — 2 passing and 1 rushing. Buffalo’s defense was relentless, forcing 3 turnovers, including 2 interceptions off QB Aaron Rodgers.

The Patriots dropped their sixth straight game in Week 17, losing 40-7 to the LA Chargers. They failed to cover as 6-point home underdogs as the Over 41.5 hit comfortably. New England’s offense mustered only 181 total yards (85 passing, 96 rushing) while their defense allowed 428 yards.

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Bills at Patriots odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 1:01 a.m. ET.

  • Moneyline (ML): Bills -135 (bet $135 to win $100) | Patriots +115 (bet $100 to win $115)
  • Against the spread (ATS): Bills -2.5 (-110) | Patriots +2.5 (-110)
  • Over/Under (O/U): 41 (O: -110 | U: -110)

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2024 betting stats

  • ML: Bills 13-3 | Patriots 3-13
  • ATS: Bills 10-6 | Patriots 6-9-1
  • O/U: Bills 10-5-1 | Patriots 10-6

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Bills vs. Patriots head-to-head

The Patriots lead the all-time series 78-51-1.

Buffalo has won 5 of the last 6 matchups, but New England has covered the spread in the last 3 meetings, including their first meeting this season on Dec. 22 in Buffalo. The Bills squeaked out a 24-21 win with the Patriots covering as 14-point underdogs. The Under 47.5 hit.

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