The Buffalo Bills (8-3) visit the AFC East rival New England Patriots (6-5) for Thursday Night Football in Week 13. Kickoff from Gillette Stadium is at 8:15 p.m. ET (Prime Video). Below, we look at Bills vs. Patriots odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
Buffalo picked up a 28-25 road victory at the Detroit Lions on Thanksgiving. QB Josh Allen had 253 passing yards with 2 TDs and 1 INT while pacing the Bills with 78 rushing yards and a score on 10 carries. WR Isaiah McKenzie led the team with 96 receiving yards on 6 receptions.
The Bills failed to cover as 10-point favorites in their 2nd straight game at Ford Field, and are 1-4 against the spread (ATS) over their last 5 games.
New England lost 33-26 at the Minnesota Vikings in the Thanksgiving nightcap. QB Mac Jones threw for a career-high 382 yards and had 2 TD against 0 INT, RB Rhamondre Stevenson had 36 yards on 7 carries as backfield mate RB Damien Harris left the game with a thigh injury.
The loss as a 2.5-point underdog ended a streak of 3 straight ATS victories.
Also see: All Week 13 odds and lines
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Bills at Patriots odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:47 p.m. ET.
- Moneyline (ML): Bills -220 (bet $220 to win $100) | Patriots +190 (bet $100 to win $190)
- Against the spread (ATS): Bills -5 (-108) | Patriots +5 (-112)
- Over/Under (O/U): 44 (O: -106 | U: -114)
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2022 betting stats
- ML: Bills 8-3 | Patriots 6-5
- ATS: Bills 5-5-1 | Patriots 6-4-1
- O/U: Bills 3-8 | Patriots 5-6
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Bills vs. Patriots head-to-head
The Pats hold a 77-47-1 lead over their longtime divisional rival in a series that dates back to 1960, including a 1-1 split in the postseason. New England took 35 of 39 meetings between Dec. 17, 2000, and Dec. 21, 2019. However, Buffalo has taken 4 of the last 5 battles, including a 47-17 victory in an AFC Wild Card playoff game last season.
While the Patriots won the first regular-season contest last year, a 14-10 victory in Week 13, the Bills outscored them 80-38 over the last 2 meetings.
Buffalo holds a slight 5-4-1 ATS advantage in the last 10 head-to-head meetings, while the Over/Under has split 5-5 along that span.
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