The Arizona Cardinals (2-3) are on the road in Week 6 to face the Seattle Seahawks (2-3) in an NFC West division game. Kickoff is Sunday at 4:05 p.m. ET (FOX). Below, we look at Cardinals vs. Seahawks odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
The Cardinals are coming off a tough 20-17 loss to the undefeated Philadelphia Eagles Sunday. K Matt Ammendola missed a 43-yard field goal with 22 seconds remaining in the game that would have tied the game and sent it to overtime. The Cardinals are 2-0 on the road, 0-3 at home this season and have lost 8 straight games at State Farm Stadium.
The Seahawks continued their offensive success but lost to the New Orleans Saints 39-32 on the road in Week 5. QB Geno Smith passed for 268 yards and 3 touchdowns in the loss, but the defense allowed 235 rushing yards, as Taysom Hill rushed for 112 yards and 3 touchdowns, and RB Alvin Kamara added 194 total yards from scrimmage.
Also see: All Week 6 odds and lines
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Cardinals at Seahawks odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:50 a.m. ET.
- Moneyline (ML): Cardinals -140 (bet $140 to win $100) | Seahawks +117 (bet $100 to win $117)
- Against the spread (ATS): Cardinals -2.5 (-117) | Seahawks +2.5 (-103)
- Over/Under (O/U): 51.5 (O: -105 | U: -115)
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2022 betting stats
- ML: Cardinals 2-3 | Seahawks 2-3
- ATS: Cardinals 3-2 | Seahawks 2-3
- O/U: Cardinals 1-3-1 | Seahawks 3-2
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Cardinals vs. Seahawks head-to-head
This will be the 47th time the teams have played. The Seahawks lead the all-time series 23-22-1. Since realignment in 2002 when they both joined the NFC West, the Seahawks lead 22-17-1.
They have split the season series each of the last 3 years.
The Cardinals are 6-2 in Seattle in the last 8 meetings there.
Cardinals QB Kyler Murray is 2-3 in 5 career starts against Seattle.
Smith has never started a game in his career against the Cardinals.
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