First look: Arizona Cardinals at Las Vegas Raiders odds and lines

Looking at Sunday’s Arizona Cardinals at Las Vegas Raiders Week 2 NFL odds, lines and trends. Here’s what you need to know.

The Arizona Cardinals (0-1) face an AFC West opponent for the second straight week as they travel to take on the Las Vegas Raiders (0-1) Sunday.  Kickoff for the Raiders’ home opener at Allegiant Stadium is 4:25 p.m. ET (CBS). Below, we look at Cardinals vs. Raiders odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Cardinals were blown out in Week 1 at home 44-21 by the Kansas City Chiefs. The Arizona defense allowed 488 total yards and Chiefs QB Patrick Mahomes threw 5 touchdown passes.

The Raiders lost their home opener on the road 24-19 to the Los Angeles Chargers. Raiders QB Derek Carr was picked off 3 times and sacked 6 times. Chargers QB Justin Herbert threw 3 TDs in the L.A. win.

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Cardinals at Raiders odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:59 p.m. ET.

  • Money line (ML): Cardinals +190 (bet $100 to win $190) | Raiders -230 (bet $230 to win $100)
  • Against the spread (ATS): Cardinals +5.5 (-110) | Raiders -5.5 (-110)
  • Over/Under (O/U): 51.5 (O: -115 | U: -105)

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2022 betting stats

  • ML: Cardinals 0-1 | Raiders 0-1
  • ATS: Cardinals 0-1 | Raiders 0-1
  • O/U: Cardinals 1-0 | Raiders 0-1

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Cardinals vs. Raiders head-to-head

Dating back to 1973, the Cardinals and Raiders have only played 10 times. The Raiders have a slight 6-4 lead in the all-time series.

They last met in 2018 and the Raiders won that game 23-21 on a last-second 35-yard field goal by Daniel Carlson.

This will be the first time the two teams have played each other in the regular season in Las Vegas.

Carr is 1-1 in his career against the Cardinals. This will be QB Kyler Murray’s 1st career game in the regular season against the Raiders.

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