First look: Arizona Cardinals at LA Rams odds and lines

Looking at Saturday’s Arizona Cardinals at L.A Rams Week 17 NFL odds, lines and trends. Here’s what you need to know.

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The Arizona Cardinals (7-8) take on the LA Rams (9-6) in Week 17 in one of 3 Saturday games on the schedule. Kickoff is at 8:15 p.m. ET from SoFi Stadium (NFL Network). Below, we look at Cardinals vs. Rams odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Cardinals lost for the fourth time in 5 games on Sunday, falling on the road to the Carolina Panthers 36-30 in overtime as 5.5-point favorites. The loss, coupled with the Rams’ win on Sunday, eliminated them from playoff contention.

The Rams hold a 1-game lead in the NFC West over the Seattle Seahawks. They won their fourth consecutive game, beating the New York Jets 19-9 on the road and covering the 3-point spread as favorites.

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Cardinals at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 10:46 a.m. ET.

  • Moneyline (ML): Cardinals +200 (bet $100 to win $200) | Rams -250 (bet $250 to win $100)
  • Against the spread (ATS): Cardinals +6 (-110) | Rams -6 (-110)
  • Over/Under (O/U): 48.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Cardinals 7-8 | Rams 9-6
  • ATS: Cardinals 9-6 | Rams 8-7
  • O/U: Cardinals 7-7-1 | Rams 7-8

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Cardinals vs. Rams head-to-head

The teams met in Week 2 in Arizona with the Cardinals blowing them out 41-10. Since Sean McVay became the Rams coach, LA is 13-3 against Arizona.

The Cardinals have not swept a season series since 2014.

The Rams lead the all-time series 50-41-2.

Cardinals QB Kyler Murray is 2-7 in 9 regular-season appearances against the Rams.

Rams QB Matthew Stafford is 7-6-1 in 14 regular-season starts against the Cardinals, including when he was with the Detroit Lions.

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