Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 10 gameday inactives, weather and notes
KEY GAME-TIME DECISIONS
Early games: QB Trevor Lawrence, WR Brian Thomas Jr., WR Deebo Samuel
Afternoon games:
Sunday night:
Monday night: WR Tyreek Hill
Early games
New York Giants at Carolina Panthers in Munich (9:30 a.m. ET)
Kickoff Weather: 41°F, cloudy
Giants
Inactives: CB Jason Pinnock, DT Jordon Riley, QB Tommy DeVito, WR Darius Slayton, LB Darius Muasau, WR Bryce Ford-Wheaton and OG Jake Kubas
Lineup notes: WR Darius Slayton (concussion) is out. PK Graham Gano (hamstring) was activated from IR on Saturday.
Panthers
Inactives: DE Charles Harris, OT Ikem Ekwonu, CB Shemar Bartholomew, DT Jaden Crumedy, TE Tommy Tremble, S Jammie Robinson and RB Jonathon Brooks
Lineup notes: WR Adam Thielen (hamstring) is out again. RB Jonathon Brooks (knee) is inactive despite being close to playing. TE Ja’Tavion Sanders (wrist, ankle) managed a full session in Friday and will start at tight end. OT Ikem Ekwonu (ankle) is out.
New England Patriots at Chicago Bears (1:00 p.m. ET)
Kickoff Weather: 58°F, clear, SSW 12 mph
Patriots
Inactives:
Lineup notes: S Kyle Dugger (ankle) will not play.
Bears
Inactives:
Lineup notes: CB Jayon Jones (shoulder) was placed on IR. S Jaquan Brisker (concussion), LT Braxton Jones (knee) and RT Darnell Wright (knee) are out.
Buffalo Bills at Indianapolis Colts (1:00 p.m. ET)
Kickoff Weather: 64°F, mostly cloudy (retractable-roof dome)
Bills
Inactives:
Lineup notes: WR Keon Coleman (wrist) has been ruled out. WR Amari Cooper (wrist) is questionable after limited work all week. TE Dalton Kincaid (knee) and QB Josh Allen (hand) practiced all week and will play.
Colts
Inactives:
Lineup notes: C Ryan Kelly (knee) went on IR with a knee injury. WR Michael Pittman Jr. (back, finger) also is out.
Denver Broncos at Kansas City Chiefs (1:00 p.m. ET)
Kickoff Weather: 55°F, clear, WNW 11 mph
Broncos
Inactives:
Lineup notes: No injuries of fantasy relevance.
Chiefs
Inactives:
Lineup notes: RB Isiah Pacheco (leg), WR Rashee Rice (knee) and WR Skyy Moore (abdomen) are on IR. WR JuJu Smith-Schuster (hamstring) also is out. RB Kareem Hunt (quadriceps), WR Mecole Hardman (shoulder, knee) and QB Patrick Mahomes (ankle) all practiced Friday and will play.
Atlanta Falcons at New Orleans Saints (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Falcons
Inactives:
Lineup notes: WR Drake London (hip) is questionable after limited practices all week. He’s expected to play. LB Troy Andersen (knee) practiced all week and will play.
Saints
Inactives:
Lineup notes: RB Kendre Miller (hamstring) landed back on IR with an injury to the hamstring in his other leg. WR Chris Olave (concussion) will join him, and WR Cedrick Wilson (shoulder) was ruled out. RB Jamaal Williams (groin) is questionable. QB Derek Carr (illness) and RB Alvin Kamara (hand) practiced all week and will play.
San Francisco 49ers at Tampa Bay Buccaneers (1:00 p.m. ET)
Kickoff Weather: 82°F, cloudy, ESE 10 mph
49ers
Inactives:
Lineup notes: RB Christian McCaffrey (Achilles) is questionable but had a full practice Friday and is expected to play after Saturday’s activation from IR. WR Deebo Samuel (rib, oblique) and DE Nick Bosa (hip) are questionable after limited work Friday. RB Jordan Mason (shoulder), PK Jake Moody (ankle) and WR Jauan Jennings (hip) practiced Friday and will go.
Buccaneers
Inactives:
Lineup notes: WR Chris Godwin (ankle) remains on IR and will miss the rest of the season. WR Mike Evans (hamstring) is out again WR Jalen McMillan (hamstring) is questionable after limited work Friday. RB Bucky Irving (toe), WR Sterling Shepard (hamstring, hip) and QB Baker Mayfield (toe) will all play.
Pittsburgh Steelers at Washington Commanders (1:00 p.m. ET)
Kickoff Weather: 60°F, cloudy, S 11 mph
Steelers
Inactives:
Lineup notes: No injuries of fantasy relevance.
Commanders
Inactives:
Lineup notes: CB Marshon Lattimore (hamstring) and RB Brian Robinson Jr. (hamstring) are out. PK Austin Seibert (hip) was downgraded to out, so PK Zane Gonzalez will handle the kicking chores. RT Andrew Wylie (shoulder) remains questionable. RB Chris Rodriguez Jr. was elevated to the active roster.
Minnesota Vikings at Jacksonville Jaguars (1:00 p.m. ET)
Kickoff Weather: 77°F, cloudy
Vikings
Inactives:
Lineup notes: LB Blake Cashman (toe) and LB Ivan Pace (knee) are out.
Jaguars
Inactives:
Lineup notes: WR Christian Kirk (collarbone) remains on IR and is likely out for the season. OG Ezra Cleveland (ankle) is out again. QB Trevor Lawrence (shoulder) is listed as questionable, but there’s a large shadow of doubt that he plays. WR Brian Thomas Jr. (chest), WR Gabe Davis (shoulder) and RB Keilan Robinson (toe) are all questionable. Robinson had a full session Friday, but the other two were limited all week. RB Tank Bigsby (ankle) also was limited this week, but he doesn’t carry an injury designation. WR Devin Duvernay (hamstring) was activated from IR, but he’s questionable.
Late-afternoon window
Tennessee Titans at Los Angeles Chargers (4:05 p.m. ET)
Kickoff Weather: 68°F, clear (open-air dome)
Titans
Inactives:
Lineup notes: WR Treylon Burks (knee) remains on IR. CB L’Jarius Sneed (quad) will not play. RB Tyjae Spears (hamstring), WR Tyler Boyd (shoulder), QB Will Levis (shoulder) and RB Tony Pollard (foot) will all play. Pollard was limited Friday, but the rest were full participants. LB Joey Bosa (hip) and LB Khalil Mack (groin) are questionable.
Chargers
Inactives:
Lineup notes: RB Gus Edwards (ankle) came off IR and graduated to a full practice Friday. He’s questionable.
Philadelphia Eagles at Dallas Cowboys (4:25 p.m. ET)
Kickoff Weather: 76°F, clear
Eagles
Inactives:
Lineup notes: TE Dallas Goedert (hamstring), WR A.J. Brown (knee) and WR DeVonta Smith (hamstring) will all play. Smith was out of practice Wednesday, limited Thursday and a full-go Friday. Brown was limited Wednesday and good the rest of the week.
Cowboys
Inactives:
Lineup notes: WR Brandin Cooks (knee) remains on IR. QB Dak Prescott (hamstring) and CB DaRon Bland (foot) are out. DE Micah Parsons (ankle) upgrades to questionable this week after limited practices and will play, per reports. WR CeeDee Lamb (shoulder) and RG Zack Martin (shoulder) were limited early in the week but worked in full Friday and will play.
New York Jets at Arizona Cardinals (4:25 p.m. ET)
Kickoff Weather: 77°F, clear (retractable-roof dome)
Jets
Inactives:
Lineup notes: TE Tyler Conklin (ankle) and RT Morgan Moses (knee) are questionable. Both practiced Friday, alongside QB Aaron Rodgers (knee, hamstring), who will start.
Cardinals
Inactives:
Lineup notes: PK Matt Prater (knee) remains on IR. RB James Conner (finger) practiced Friday and will play.
Sunday Night Football
Detroit Lions at Houston Texans (8:20 p.m. ET)
Kickoff Weather: 77°F, clear (retractable-roof dome)
Lions
Inactives:
Lineup notes: LT Taylor Decker (shoulder) is out.
Texans
Inactives:
Lineup notes: WR Stefon Diggs (hamstring) is out for the year with a torn ACL. DE Will Anderson (ankle) and RB Dameon Pierce (groin) are out. WR Nico Collins (hamstring) and WR Tank Dell (back) questionable after limited work Friday. Collins was activated from IR on Saturday, and both receivers are expected to play.
Monday Night Football
Miami Dolphins at Los Angeles Rams (8:15 p.m. ET)
Kickoff Weather: 61°F, clear (open-air dome)
Dolphins
Lineup notes: WR Tyreek Hill (wrist) didn’t practice Friday. Watch his participation level Saturday. RT Austin Jackson (knee) will not be available to protect QB Tua Tagovailoa‘s blindside.
Rams
Lineup notes: TE Tyler Higbee (knee) remains on the PUP. WR Jordan Whittington (shoulder) and WR Demarcus Robinson (toe, hip) avoided injury tags.