The season opens for the Duke Blue Devils and the Notre Dame Fighting Irish Saturday at Notre Dame Stadium in South Bend, Ind., for a 2:30 p.m. ET kickoff. We analyze the Duke-Notre Dame college football betting odds and lines, with picks and best bets.
The Irish are ranked No. 10 in the Amway Coaches Poll powered by USA TODAY Sports.
Duke at Notre Dame: Betting odds and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 2:45 a.m. ET.
- Moneyline: Notre Dame -1112 | Duke +660
- Against the spread/ATS: Notre Dame -20.5 (-110) | Duke +20.5 (-110)
- Over/Under: 54.5 (O: -110 | U: -110)
Duke at Notre Dame: Three things to know
- The last time the Blue Devils paid a visit to South Bend, they came away with a thrilling 38-35 victory as 19 1/2-point underdogs on Sept. 24, 2016. Current New York Giants QB Daniel Jones threw for 290 yards and three touchdowns in the upset. Notre Dame returned the favor at Wallace Wade Stadium in Durham, N.C., last season, winning 38-7.
- Duke starting long snapper Ben Wyatt, LB Brandon Hill and RB Myles Hudzick are key players to opt out due to COVID-19 concerns. Reserve OT Jacob Rimmer also is sitting out.
- Former Clemson starter QB Chase Brice is likely to take the reins of the Duke offense for head coach David Cutcliffe. QB Ian Book is back for Notre Dame, starting in his graduate season.
Get some action on this game or any other matchup with a college football bet at BetMGM in NJ, IN, CO and WV. Bet now!
Duke at Notre Dame: Odds, betting lines and picks
Prediction
Notre Dame 37, Duke 20
Moneyline (ML)
Picking Notre Dame (-1112) will require you to put up a little more than 11 times your potential return – a winning $10 bet will only profit $0.90. That’s a poor gambling strategy over the long term. AVOID.
Also see:
- Notre Dame depth chart (Fighting Irish Wire)
- CFN – The latest college football coverage
Against the spread (ATS)
DUKE +20.5 (-110) worked during the offseason to bolster its offensive line, and the addition of Brice as the signal caller will give the Blue Devils a functional offense. They aren’t likely to spring an upset over Notre Dame for a second straight time in South Bend, but they should be able to hang within three touchdowns.
Over/Under (O/U)
The OVER 54.5 (-110) is a good play, as Duke’s defense allowed 29.2 points per game last season, and it isn’t expected to be a whole lot better on that side of the ball. This one won’t be a track meet, but the total should be in the high 50’s.
Want some action in this one? Place a bet at BetMGM now. For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.
Follow @JoeWilliamsVI on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage.
[lawrence-newsletter]
[lawrence-auto-related count=3 category=1622]