Detroit Tigers at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Detroit Tigers at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Detroit Tigers (45-74) and the Cleveland Guardians (62-55) wrap up a 4-game set Wednesday at Progressive Field. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Tigers vs. Guardians odds with MLB picks and predictions.

Season series: Tied 9-9

After a 4-1 setback in Game 1 of a doubleheader Monday, the Tigers bounced back with a 7-5 win in Game 2, and a 4-3 victory Tuesday. Both teams have scored 12 runs apiece despite that Detroit has won 2 of the 3 games.

The Guardians remain in 1st place in the AL Central Division despite losing the past 2 outings. Their performance over their last 2 games is a disappointment after an 8-1 run from Aug. 6-15.

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Tigers at Guardians projected starters

LHP Daniel Norris vs. RHP Cal Quantrill

Norris (0-4, 5.97 ERA) makes his 3rd start and 29th appearance. He has a 1.44 WHIP, 6.0 BB/9 and 11.4 K/9 in 34 2/3 IP.

  • Allowed just 4 H and 2 BB with 1 K in 4 2/3-scoreless IP in a no-decision at the Chicago White Sox Friday in his first outing with the Tigers after coming over from the Chicago Cubs.
  • Has an 0-2 record with a 3.86 ERA in 25 2/3 IP with a .200 opponent batting average over 21 nighttime games vs. a 0-2 record, 12.00 ERA and .250 opponent BA in 7 daytime appearances.

Quantrill (9-5, 3.67 ERA) makes his 23rd start. He has a 1.22 WHIP, 2.4 BB/9 and 6.0 K/9 in 130 IP.

  • Picked up his career-high 9th win with 7-scoreless IP and just 1 H and 0 BB allowed at the Toronto Blue Jays Friday.
  • Has won 5 straight decisions across his past 7 starts dating back to  a July 5 loss in Detroit.
  • Is 1-1 with a 2.70 ERA with 9 K across 10 IP over 2 starts vs. Detroit this season.

Tigers at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:43 a.m. ET.

  • Money line (ML): Tigers +175 (bet $100 to win $175) | Guardians -220 (bet $220 to win $100)
  • Run line (RL)/Against the spread (ATS): Tigers +1.5 (-120) | Guardians -1.5 (+100)
  • Over/Under (O/U): 7.5 (O: -122 | U: -102)

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Tigers at Guardians picks and predictions

Prediction

Guardians 5, Tigers 2

Money line

The Guardians (-220) will cost more than 2 times your potential return, and over the long haul that’s just not a good betting strategy.

AVOID, and look to the run line instead.

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Run line/Against the spread

The GUARDIANS -1.5 (+100) are a much better play on the run line at home. Quantrill has been on fire lately with his last loss coming in early July. It just so happens that the last loss was against the Tigers. However, he also dominated them with 6-scoreless IP in a win July 16 last time they met.

Over/Under

The UNDER 7.5 (-102) is worth a look in the series finale.

The Under has been the dominant trend for both of these clubs. It’s 8-2-1 in the past 11 games overall for the Guardians and 4-1 in their last 5 games at home.

The Under is 13-3-5 in the past 21 games overall for the Tigers while going 8-2-2 in the previous 12 outings inside the division.

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