Detroit Pistons at Boston Celtics odds, picks and predictions

Analyzing Wednesday’s Detroit Pistons at Boston Celtics odds and lines, with NBA expert picks, predictions and best bets.

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The Detroit Pistons (9-14) and Boston Celtics (17-4) meet Wednesday. Tip-off from TD Garden is set for 7:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Pistons vs. Celtics odds and make our expert NBA picks and predictions for the best bets.

Season series: Celtics lead 1-0

The Pistons are coming off a 128-107 loss as 3-point underdogs vs. the visiting Milwaukee Bucks Tuesday with the Over (222) hitting. Detroit is just 2-6 straight up (SU) and 1-7 against the spread (ATS) in its last 8 games.

The Celtics won 108-89 as 9.5-point home favorites vs. the Miami Heat Monday as the Under (220) cashed. F Jaylen Brown scored a game-high 29 points, and G Payton Pritchard added 25 off the bench.

In an Oct. 26 meeting, the Pistons covered as 12.5-point home underdogs in a 124-118 Celtics win while the Over (225) hit. Celtics F Jayson Tatum led all scorers with 37 points, but is questionable for Wednesday with a knee injury.

Pistons at Celtics odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 1:35 p.m. ET.

  • Moneyline (ML): Pistons +750 (bet $100 to win $750) | Celtics -1200 (bet $1,200 to win $100)
  • Against the spread (ATS): Pistons +13.5 (-110) | Celtics -13.5 (-110)
  • Over/Under (O/U): 221.5 (O: -110 | U: -110)

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Pistons at Celtics key injuries

Pistons

  • None

Celtics

  • Jrue Holiday (knee) questionable
  • Jayson Tatum (knee) questionable

For most recent updates: Official NBA injury report.

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Pistons at Celtics picks and predictions

Prediction

Celtics 117, Pistons 111

Moneyline

The Celtics (-1200) have won the last 10 meetings, but laying -1200 on an ML in the NBA isn’t realistic.

PASS. Bet the spread and/or total instead.

Against the spread

The Pistons have been lighting tickets on fire lately, but the Celtics haven’t been much better.

Boston is 2-6 ATS in its last 8 games, and while it’s been winning SU, it’s been having trouble covering as a favorite. Holiday isn’t 100 percent, Tatum isn’t 100 percent, and the Celtics have been struggling to win by margin — take Detroit.

BET PISTONS +13.5 (-110).

Over/Under

The Over (225) hit in the Oct. 26 meeting, with the Pistons surprisingly putting up 118 points. Detroit’s offense has been inconsistent, but it has scored 111 or more in 5 of its last 9 games.

Boston just beat Miami (in a rematch of a first-round playoff series from last season), and its next game is vs. the Bucks. How focused will it be on defense against a struggling Detroit squad?

BET OVER 221.5 (-110).

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