The Dallas Cowboys and Tampa Bay Buccaneers open the regular season Thursday night. Kickoff at Raymond James Stadium is scheduled for 8:20 p.m. ET. Below, we look at the Cowboys vs. Buccaneers odds and lines, and make our best NFL picks, predictions and bets.
Cowboys QB Dak Prescott suffered a gruesome ankle fracture last season which derailed what looked to be a very promising campaign. He’s back, and reportedly at full speed.
Buccaneers QB Tom Brady starts his second full season under center in Tampa, and he is looking to pick up right where he left off. The Tampa Bay offense has all 11 starters back after its championship season.
Also see: NFL team win totals, playoff lines and Super Bowl odds
Cowboys at Buccaneers odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 6:40 a.m. ET.
- Money line: Cowboys +320 (bet $100 to win $320) | Buccaneers -420 (bet $420 to win $100)
- Against the spread (ATS): Cowboys +8.5 (-110) | Buccaneers -8.5 (-110)
- Over/Under (O/U): 51.5 (O: -108 | U: -112)
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Cowboys at Buccaneers key injuries
Cowboys
- OG Zack Martin (COVID-19) out
- QB Dak Prescott (ankle, shoulder) expected to play
Buccaneers
- S Jordan Whitehead (hamstring) out
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Cowboys at Buccaneers odds, lines, predictions and picks
Prediction
Buccaneers 31, Cowboys 24
Money line
The Buccaneers (-400) will cost you four times your potential return, and that’s entirely too much, even on Brady and the defending champs.
AVOID, and look to the spread instead.
Against the spread
The good news for the COWBOYS +8.5 (-110) is that Prescott is back under center and expected to be a full go from the jump. The bad news is that they open on the road against the defending champs.
I don’t think Prescott and the ‘Boys can shock the world and start the NFL season with a big money line upset, but I do think they have enough offensive weapons to keep this a one-score game.
Over/Under
The OVER 51.5 (-108) might be the best play on the board. The Cowboys are going to want to air it out early and often, and Prescott has several top-notch targets in WRs Amari Cooper, CeeDee Lamb and Michael Gallup. Dallas should be able to keep pace with Brady and the Bucs in an entertaining game to start the season.
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