Dallas Cowboys at Los Angeles Chargers odds, picks and prediction

Analyzing Saturday’s Dallas Cowboys at Los Angeles Chargers preseason odds and lines, with expert NFL picks, predictions and best bets.

The Dallas Cowboys and Los Angeles Chargers meet in preseason action Saturday. Kickoff from SoFi Stadium is scheduled for 10 p.m. ET (NFL Network). Below, we analyze Tipico Sportsbook‘s lines around the Cowboys vs. Chargers odds, and make our best NFL picks, predictions and bets.

The Cowboys opened the preseason with a 17-7 loss on the road against the Denver Broncos. Now they face another AFC West foe in their building.

QB Will Grier, battling with QB Cooper Rush for the backup job, missed the preseason opener due to a hamstring injury. He is expected to play, which likely means if we see starting QB Dak Prescott, it will be a cameo at best.

The Chargers fell to the defending Super Bowl-champ Los Angeles Rams at SoFi last weekend, 29-22. Veteran backup QB Chase Daniel tossed a pair of touchdowns, and the offense is still in good hands if starting QB Justin Herbert is limited or held out.

Cowboys at Chargers odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:50 a.m. ET.

  • Money line (ML): Cowboys +155 (bet $100 to win $155) | Chargers -190 (bet $190 to win $100)
  • Against the spread (ATS): Cowboys +3.5 (-117) | Chargers -3.5 (-103)
  • Over/Under (O/U): 37.5 (O: -105 | U: -115)

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Cowboys at Chargers picks and predictions

Prediction

Chargers 20, Cowboys 17

Money line

The Chargers (-190) should be able to bounce back to grab their first win of the preseason, as Daniel and third-string QB Easton Stick were able to move the offense last weekend. Still, this is a hefty amount of chalk to eat for a preseason game, especially one that should be fairly close.

AVOID.

Against the spread

The COWBOYS +3.5 (-117) are worth a look catching 3 and a hook. The offense was rather moribund last weekend in the Mile High City, with most of the offense, and all of the scoring, coming from QB Ben DiNucci in the fourth quarter. Expect Grier, Rush and company to be a little better in Saturday’s game.

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Over/Under

The UNDER 37.5 (-115) might seem a bit risky after the Over cashed at a 13-3 clip in the opening weekend of preseason action. However, defense has reigned supreme so far in Week 2, going 3-1 through Thursday’s and Friday’s action.

The Cowboys managed just 7 points and hit one of those rare Unders in Week 1 action. While I expect them to be a little better, I still think defense rules the day here.

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