Creighton at Villanova odds, picks and prediction

Previewing Wednesday’s Creighton Bluejays at Villanova Wildcats odds and lines, with college basketball betting picks, tips and predictions.

The Creighton Bluejays (17-6 overall, 13-5 Big East) travel to meet the Villanova Wildcats (15-4, 10-3) Wednesday at Finneran Pavilion in Bryan Mawr, Penn., for an 8:30 p.m. ET tip-off. Below, we analyze the Creighton-Villanova odds and lines, with NCAA college basketball picks and predictions.

Creighton at Villanova: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 11:55 a.m. ET.

  • Money line: Creighton +185 (bet $100 to win $185) | Villanova -225 (bet $225 to win $100)
  • Against the spread/ATS: Creighton +5.5 (-115) | Villanova -5.5 (-105)
  • Over/Under: 146.5 (O: -110 | U: -110)

Creighton at Villanova: Three things to know

  1. The Wildcats enter this game looking for redemption after a 73-61 loss at Butler Sunday. While the Wildcats are 0-3 straight up and ATS in their past three road games, they’re money at home. Villanova is 8-0 SU and 4-3-1 ATS in their eight home outings this season.
  2. The Bluejays were also tripped up last time out, falling 77-69 at Xavier as 4-point favorites. While they lost that one, they’re still 4-1 SU (2-3 ATS) across their past five games on the road. Creighton is just 2-6 ATS in its past eight games on the road, including 1-4 ATS in the past five on the road against teams with a winning home record.
  3. Villanova is a good offensive club, going for 77.2 points per game to rank 56th in the country. The Wildcats are also a good free-throw shooting team at 78.2% to rank 15th in the country. Defensively, the Wildcats have struggled against 3-pointers, allowing opponents to hit 35.9%, good for just 295th overall in the nation.

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Creighton at Villanova: Odds, lines, predictions and picks

Prediction

Villanova 81, Creighton 74

Money line (ML)

VILLANOVA (-225) is over my usual money line limit of -180, but the Wildcats are a solid bet on their home floor. The Wildcats haven’t lost in eight games at home, and they will have revenge on their minds after losing at Creighton Feb. 13.

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Against the spread (ATS)

VILLANOVA -5.5 (-105) is a good bet on its home floor, especially since Creighton has struggled so much on the road, at least against the number.

You’ll be betting against some serious trends, as the road team has cashed in four of the past five games in this series, with the underdog going 6-0 ATS.

Over/Under (O/U)

OVER 146.5 (-110) is the best play on the board. Villanova has been crushing Overs lately, going 6-1 in its past seven at home, and 9-4 in its previous 13 games overall.

Creighton has rolled up 78.6 PPG on offense, ranking 39th in the nation, so they can hang with anyone. They will make you pull your hair out with their struggles at the free-throw line, as they hit just 65.7% of free throws, but we should see the Over inch across the line regardless.

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