Colts vs. Texans: Staff picks and predictions for Week 1

Here are the staff picks and predictions for the Colts’ Week 1 matchup.

The Indianapolis Colts (0-0) are on the road to begin the 2022 regular season with a divisional bout at NRG Stadium against the Houston Texans (0-0) in Week 1.

The Colts have not won an opening day matchup to begin the campaign since the 2013 season.

The expectation is that they will come out with a win, though. Vegas currently has the Colts favored with the largest spread of the week while the experts around the league have all chosen to side with Indy coming out victorious.

Here’s how the Colts Wire staff feels about the outcome of the game: