The Indianapolis Colts (4-5) are set to host the Jacksonville Jaguars (2-6) at Lucas Oil Stadium for a Week 10 divisional matchup.
Entering the weekend, the Colts are heavy favorites for this matchup at home in what will be the first meeting with the Jaguars and rookie quarterback Trevor Lawrence.
Here’s how the experts around the league are picking this matchup:
| Expert | Pick | Score (if applicable) |
| Nate Davis (USA TODAY) | Colts | 31-16 |
| Mike Jones (USA TODAY) | Colts | 24-16 |
| Jarrett Bell (USA TODAY) | Colts | 27-17 |
| Mike Clay (ESPN) | Colts | N/A |
| Gregg Rosenthall (NFL Network) | Colts | 33-17 |
| Vinnie Iyer (Sporting News) | Colts | 31-17 |
| Dave Richard (CBS Sports) | Colts | N/A |
| Pete Prisco (CBS Sports) | Colts | 21-14 |
| Jay Johnson (Jaguars Wire) | TBD | TBD |
| Cam DaSilva (Sportsbook Wire) | Colts | N/A |
| Bleacher Report | Colts | 31-16 |
It shouldn’t be a shock that the Colts are heavy favorites for this divisional matchup. Both teams may be under .500 but the Colts are the better team and should be expected to win this matchup.
It will be interesting to see how the secondary holds up against the rookie in Lawrence, who has yet to enjoy a breakout game.
As long as the Colts don’t do too much to hurt themselves, they should walk away with a divisional win.
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