The Indianapolis Colts (8-6) are set for a cross-conference matchup with the Arizona Cardinals (10-4) on Saturday night at State Farm Stadium in Week 16.
While Vegas currently has the Colts sitting as underdogs in this matchup by 1.5 points, the experts around the league are siding with Indy to take this road matchup.
The Colts will be without all three of their starting interior offensive linemen and a starting cornerback due to COVID-19 issues. Even so, Jonathan Taylor and the Colts will be looking to take down one of the best teams in the NFC.
Here’s how the Colts Wire staff feels about this matchup: