The Indianapolis Colts (0-0) are set to visit the Houston Texans (0-0) are NRG Stadium to begin the 2022 NFL season Sunday.
Opening the week as the biggest favorite in the league, according to Tipico Sportsbook, the spread will remain the same for the Colts. They enter this Week 1 matchup as strong favorites over the Texans and will go into the weekend looking to snap a long losing streak on opening day.
Here are the updated odds for the Week 1 matchup:
| Spread | Moneyline | Total Points | |
| Indianapolis Colts (0-0) | -7.5 | -340 | O 45.5 -115 |
| Houston Texans (0-0) | +7.5 | +270 | U 45.5 -105 |
Since the odds opened earlier in the week, the moneyline for the Colts dropped slightly. The same goes for the total score of the game, which fell one point since the odds opened.
The spread being so large may have some bettors wanting to take the Texans to cover. However, the Colts outscored the Texans 62-3 in their two games during the 2021 season.
The Colts are widely viewed as strong favorites to start their season out 1-0 and as long as they don’t get in their own way, it should come to fruition.
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