The Indianapolis Colts (0-0-1) will roll into TIAA Bank Field as road favorites over the Jacksonville Jaguars (0-1) in Week 2.
Opening the week as favorites, the Colts will remain 3.5-point road favorites over a team they haven’t beaten on the road since the 2014 season.
From Tipico Sportsbook, here are the updated betting odds going into the weekend:
| Spread | Moneyline | Total Points | |
| Indianapolis Colts (0-0-1) | -3.5 | -165 | — |
| Jacksonville Jaguars (0-1) | +3.5 | +140 | — |
While the spread is still the same as the opening odds this week, the moneyline shifted slightly more in favor of the Jaguars.
The Colts also are dealing with several injuries on both sides of the ball already. Wide receiver Michael Pittman Jr., defensive tackle DeForest Buckner and cornerback Kenny Moore II are all questionable for the game.
Both teams are looking for their first win of the season and even though the Colts are favored, this game won’t be an easy one for the road team.
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