The Colorado Rockies (51-62) and Houston Astros (67-46) close out an abbreviated two-game set Wednesday with a 2:10 p.m. ET first pitch at Minute Maid Park. Let’s analyze the lines around the Rockies vs. Astros odds with MLB picks and predictions.
RHP Antonio Senzatela is the projected starting pitcher for the Rockies. He is 2-8 with a 4.73 ERA, 1.41 WHIP, 6.5 K/9 and 2.0 BB/9 through 99 IP over 18 starts.
- Is making his second start back off the injured list. The Colorado hurler has struggled away from home with a 6.03 road ERA in 2021, and he owns a 6.17 road mark since 2019.
LHP Framber Valdez is the projected starter for the Astros. Through 13 starts, he is 7-3 with a 3.22 ERA, 1.30 WHIP, 8.4 K/9 and 4.1 BB/9 across 78 1/3 IP.
- Has struggled after getting off to a hot start. He owns a 4.30 ERA and 1.52 WHIP over his last 46 IP.
- Facing a left-leaning Rockies lineup and that bodes well for the southpaw who has held lefty bats to a .600 OPS over his career.
Rockies at Astros odds, lines, picks and prediction
MLB odds courtesy of Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 11:45 a.m. ET.
- Money line: Rockies +220 (bet $100 to win $220) | Astros -280 (bet $280 to win $100)
- Against the spread/ATS: Rockies +2.5 (-130) | Astros -2.5 (+105)
- Over/Under: 9.5 (O: +100 | U: -125)
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Prediction
Astros 5, Rockies 3
Money line (ML)
Colorado went into this two-gamer off a 5-1 homestand. Now, the Rockies find themselves back on the road where they struggle more than any other major league team. After losing Tuesday’s series opener, Colorado is just 13-41 with a minus-102 run differential away from Denver. Offensively, the club’s .614 road OPS ranks last in the league.
Houston, conversely, has been quite good at home. After Tuesday’s 5-0 triumph, the Astros are 36-23 at Minute Maid.
So, Houston is a worthy favorite and a worthy heavy favorite; however, the wide gulf in prices here makes for an easy PASS.
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Run line/Against the spread (ATS)
There isn’t much of a lean here, but the price makes for some interest in the ASTROS -1.5 (-135) on the alternate run line. Houston has much the better bullpen, and that relief corps is a hedge on the risk of a multi-run victory.
Over/Under (O/U)
The Rockies’ road batting stats and Houston’s bullpen numbers go into a mix with some Statcast figures that peg both offenses as being too far out over their skis.
The Under is 5-0 in Houston’s last five interleague games against losing teams.
TAKE THE UNDER 9.5 (-125).
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