Cleveland Guardians at Los Angeles Angels odds, picks and predictions

Analyzing Wednesday’s Cleveland Guardians at Los Angeles Angels odds and lines, with MLB expert picks and predictions.

The Cleveland Guardians (7-10) and Los Angeles Angels (11-7) close out their 3-game series Wednesday at 9:38 p.m. ET at Angel Stadium. Let’s analyze Tipico Sportsbook‘s lines around the Guardians vs. Angels odds with MLB picks and predictions.

Season series: Los Angeles leads 2-0 and has outscored Cleveland 7-1.

Cleveland was swept in New York last weekend and has now lost 5 in a row. An offense that bolted quickly from the gate with favorable ball-in-play rates has sputtered over the losing skid. The Guardians have scored 1.60 runs per game on a .486 OPS in the 5 straight losses.

Los Angeles has come on strong with the bats of late. They are 10-4, averaging 5.43 runs per game with a .783 OPS in their last 14 games.

Guardians at Angels projected starters

RHP Zach Plesac vs. RHP Shohei Ohtani

Plesac (1-1, 1.53 ERA) is lined up for his fourth start of 2022. He has a 1.08 WHIP, 1.0 BB/9, and 5.1 K/9 in 17 2/3 IP.

  • Went 6 2/3 IP, allowing 2R (1 ER) Thursday against the Chicago White Sox in his last start.
  • Faced Los Angeles once last season (May 18) and allowed 5 ER in 7 IP.

Ohtani (1-2, 4.40 ERA) makes his fourth start. He has a 1.05 WHIP, 2.5 BB/9, and 16.3 K/9 in 14 1/3 IP.

  • Registered a 3.18 ERA in 130 1/3 IP — along with a .965 OPS at the plate — in his AL MVP season a year ago.
  • Logged a clunker April 14 at Texas, but bounced back with 6 shutout innings (and 12 K) April 20 at Houston.

Guardians at Angels odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:22 p.m. ET.

  • Money line: Guardians +170 (bet $100 to win $170) | Angels -210 (bet $210 to win $100)
  • Against the spread (ATS): Guardians +1.5 (-125) | Angels -1.5 (+102)
  • Over/Under (O/U): 7.5 (O: -108 | U: -112)

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Guardians at Angels picks and predictions

Prediction

Angels 4, Guardians 2

Money line

Plesac has been barreled up a bit too often in the early going. The hard contact belies a ball-in-play-rate-aided 1.53 ERA. These Angeles got to Plesac for 3 HR in a game last May. They own a .776 OPS against right-handed pitchers this season.

Ohtani has pitched around issues with his batting average on balls in play (.357) and low rate for stranding runners (58.8%).

The Angels at -200 or better is a decent play. AVOID the current tag.

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Run line/Against the spread

LOS ANGELES -1.5 (+102) is a small-to-moderate-confidence play.

Over/Under

The series overall has an Under lean. TAB THE UNDER 7.5 (-112) as being worth a look here. But perhaps only a partial-unit play is warranted, because there is some fade-the-Cleveland-starter/L.A. bullpen tilt at play.

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