Clemson at Virginia Tech odds, picks and prediction

Previewing Saturday’s Clemson Tigers at Virginia Tech Hokies sports betting odds and lines, with college football betting picks, tips and predictions.

The Clemson Tigers (8-1, 7-1 ACC) visit the Virginia Tech Hokies (4-5, 4-4) Saturday for a 7:30 p.m. ET kickoff. Below, we analyze the Clemson-Virginia Tech college football betting odds and lines, with picks and predictions.

The Tigers are No. 3 in the Amway Coaches Poll powered by USA TODAY Sports.

Clemson at Virginia Tech: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 2:43 a.m. ET.

  • Money line: Clemson -1200 (bet $1,200 to win $100) | Virginia Tech +750 (bet $100 to win $750)
  • Against the spread/ATS: Clemson -22 (-110) | Virginia Tech +22 (-110)
  • Over/Under: 66.5 (O: -110 | U: -110)

Clemson at Virginia Tech: Three things to know

  1. Clemson is coming off a 52-17 victory over Pittsburgh last week, the Tigers’ first cover in the past four outings. The Tigers are 2-1 SU on the road this season, but they covered just once in those outings. The Tigers are also on a 5-0 Over run.
  2. The Tigers offense has been a buzzsaw, posting 512.2 total yards per game to rank ninth in the country, 362.8 passing YPG to rank third and 46.1 points per game, good for fifth in the country. Defensively, they have yielded just 298.6 YPG to check in eighth, and they’re allowing just 19.2 PPG, good for 19th.
  3. Virginia Tech has dropped each of its past two home games, falling to Liberty and Miami-Florida, and it’s 0-3 SU/ATS across the past three overall. The Hokies were dusted at Pittsburgh by a 47-14 count. They are 3-1 Over in their past four.

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Clemson at Virginia Tech: Odds, betting lines, predictions and picks

Prediction

Clemson 45, Virginia Tech 17

Money line (ML)

Clemson (-1200) is a heavy favorite, and for good reason. The Tigers are sound on both sides of the football. However, you cannot risk 12 times your potential return. It’s just not a very wise long-term strategy. PASS.

Against the spread (ATS)

CLEMSON -22 (-110) has covered four of the past five in this series. The Tigers are playing good football heading into this one, while the Hokies are on a major slide. The Tigers are also 11-3 ATS in the past 14 as a road favorite, while cashing in 20 of the past 28 ACC games. The Hokies are just 2-5 ATS in the past seven league games, and 2-5 ATS in the past seven against teams with a winning overall mark.

Over/Under (O/U)

UNDER 66.5 (-110) is the play here, as Clemson can be trusted to put up a healthy amount of points, but the same cannot be said about Virginia Tech against Clemson’s stingy defense. The Hokies were blown out 47-14 in Pittsburgh last week, and you can expect a similar lopsided result here.

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