Clemson at Notre Dame odds, picks and predictions

Analyzing Saturday’s Clemson Tigers at Notre Dame Fighting Irish odds and lines, with college football expert picks and predictions.

The No. 5 Clemson Tigers (8-0) and Notre Dame Fighting Irish (5-3) clash Saturday at Notre Dame Stadium in South Bend. Kickoff is scheduled for 7:30 p.m. ET (NBC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Notre Dame odds, and make our expert college football picks and predictions.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson enters this game off back-to-back, 1-score victories followed by a Week 9 bye. The Tigers, the No. 4 team in the first College Football Playoff rankings of the season, survived a somewhat shaky defensive effort in an Oct. 15 win over Florida State (34-28). They overcame 4 turnovers in an Oct. 22 victory over Syracuse (27-21).

The Fighting Irish took down Syracuse Saturday (a week after the Orange fell to Clemson). Notre Dame easily covered a 1.5-point spread in a 41-24 triumph that saw the Irish held an opposing offense under 300 total yards (286) for a 2nd straight week and a 3rd time in 4 weeks. In total defense for the season, UND ranks 28th in FBS (334.5 yards per game).

Stream select live college football games and full replays: Get ESPN+

Clemson at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 12:01  p.m. ET.

  • Moneyline: Clemson -190 (bet $190 to win $100) | Notre Dame +155 (bet $100 to win $155)
  • Against the spread (ATS): Clemson -3.5 (-110) | Notre Dame +3.5 (-110)
  • Over/Under (O/U): 44.5 (O: -107 | U: -115)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Clemson at Notre Dame picks and predictions

Prediction

Clemson 24, Notre Dame 17

Moneyline

Its likely the true odds are buried between these prices. PASS.

Against the spread

The Notre Dame run defense may be a bit overrated when looking at analytic measures. Clemson has the ground game to take advantage of this deficit.

And look for the Tigers to finish on the plus side of the field and have the havoc-causing defense to produce a short field or two.

The lean, however, is small. Consider a partial-unit play on CLEMSON -3.5 (-110).

Over/Under

Both Clemson and Notre Dame figure as perhaps a bit too far over their skis in 3rd-down defense. The Irish have been awful in red-zone defense, allowing 20 TDs in as many trips.

The weather report calls for high winds, but figure both sides being able to have enough value drives to spiral this game into the 40s by the 4th quarter.

BACK THE OVER 44.5 (-107).

Play our free daily Pick’em Challenge and win! Play now!

Want action on this game or any other NCAA football matchup? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1622]