Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Tuesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (9-26) and Cleveland Guardians (16-17) meet in an abbreviated 2-game I-71 series which kicks Tuesday at 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Guardians odds with MLB picks and predictions.

Season series: Cleveland leads 2-0.

The Reds are coming off back-to-back losses at the Pittsburgh Pirates Saturday and Sunday, but they are still 5-3 in their last 8 games. The 5 wins are more than Cincinnati had in its first 27 games, when the Reds opened an anemic 4-23.

Cleveland dropped 2 of 3 at the Minnesota Twins last weekend, but the Guardians are back at home where they are 7-2 in their last 9 games. Over those 9 contests, Cleveland scored 50 runs.

Reds at Guardians projected starters

RHP Connor Overton vs. RHP Zach Plesac

Overton (1-0, 1.59 ERA) is tabbed for his 4th start. He has a 1.06 WHIP, 3.2 BB/9 and 4.2 K/9 in 17 IP.

  • Pitched 6 1/3 scoreless innings Thursday at Pittsburgh.
  • Has benefited from a .250 batting average on balls in play.

Plesac (1-3, 4.68 ERA) has made 6 starts. He owns a 1.35 WHIP, 2.8 BB/9 and 5.5 K/9 in 32 2/3 IP.

  • Has coughed up 17 runs over his last 15 IP.

Reds at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:56 a.m. ET.

  • Money line: Reds +135 (bet $100 to win $135) | Guardians -170 (bet $170 to win $100)
  • Run line (RL): Reds +1.5 (-155) | Guardians -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Reds at Guardians picks and predictions

Prediction

Guardians 4, Reds 2

Money line

The Reds have been woeful on the road, going 4-17 in their first 21 games away from home. Cleveland is the lean in principle, but STEER CLEAR of any tag higher than -165.

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Run line/Against the spread

CLEVELAND -1.5 (+125) is the advisable play here. But the run line favorite on a likable low total can be a tricky proposition. Consider a partial-unit play.

Since 2020, Plesac owns a 4.50 ERA on the road and a 3.63 figure at home.

Over/Under

Both sides have some surface batting stats and run-scoring numbers not fully supported by advanced analytics and batted-ball metrics. Cleveland’s offense hasn’t been terribly productive at home; the same applies for Cincinnati’s bats on the road. Mix in fresh bullpen arms and a slight inward breeze in the  Cleveland weather forecast, and a lower-scoring game here gets the lean.

BACK THE UNDER 7.5 (+105).

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