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The Kansas City Chiefs are set to face the Buffalo Bills in Week 6 of the 2022 NFL season.
It’s the game that everyone has been waiting for since last season’s thrilling AFC divisional round game. Two of the best teams going head-to-head for sole possession of first place in the AFC conference. Who will emerge victorious?
Below are important game details about this regular season matchup. If you have questions about the game, reach out to us on Twitter @TheChiefsWire.
Game information:
Who: Kansas City Chiefs vs. Buffalo Bills
When: Sunday, Oct. 16, 3:25 p.m. CT
Where: GEHA Field at Arrowhead Stadium – Kansas City, Missouri
Streaming:
In-market live stream: fuboTV (free 7-day trial)
Broadcast:
TV: KCTV-5 (CBS Kansas City)
Radio: WDAF-FM (106.5FM Kansas City)
Broadcasters:
Tony Romo, Jim Nantz and Tracy Wolfson
Referee:
Opponent wire site:
2022 Schedule:
| Week | Date | Opponent | Time | |
| 1 | Sunday, Sept. 11 | @ Arizona Cardinals | 3:25 p.m. CT on CBS | Tickets |
| 2 | Thursday, Sept. 15 | vs Los Angeles Chargers (TNF) | 7:15 p.m. CT on Amazon Prime Video | Tickets |
| 3 | Sunday, Sept. 25 | @ Indianapolis Colts | Noon CT on CBS | Tickets |
| 4 | Sunday, Oct. 2 | @ Tampa Bay Buccaneers (SNF) | 7:30 p.m. CT on NBC | Tickets |
| 5 | Monday, Oct. 10 | vs. Las Vegas Raiders (MNF) | 7:15 p.m CT on ESPN | Tickets |
| 6 | Sunday, Oct. 16 | vs. Buffalo Bills | 3:25 p.m. CT on CBS | Tickets |
| 7 | Sunday, Oct. 23 | @ San Francisco 49ers | 3:25 p.m. CT on FOX | Tickets |
| 8 | Sunday, Oct. 30 | BYE | BYE | BYE |
| 9 | Sunday, Nov. 6 | vs. Tennessee Titans (SNF) | 7:20 p.m. CT on NBC | Tickets |
| 10 | Sunday, Nov. 13 | vs. Jacksonville Jaguars | Noon CT on CBS | Tickets |
| 11 | Sunday, Nov. 20 | @ Los Angeles Chargers | 3:25 p.m. CT on CBS | Tickets |
| 12 | Sunday, Nov. 27 | vs. Los Angeles Rams | 3:25 p.m. CT on FOX | Tickets |
| 13 | Sunday, Dec. 4 | @ Cincinnati Bengals | 3:25 p.m. CT on CBS | Tickets |
| 14 | Sunday, Dec. 11 | @ Denver Broncos (SNF) | 7:20 p.m. CT on NBC | Tickets |
| 15 | Sunday, Dec. 18 | @ Houston Texans | Noon CT on CBS | Tickets |
| 16 | Saturday, Dec. 24 | vs. Seattle Seahawks | Noon CT on FOX | Tickets |
| 17 | Sunday, Jan. 1 | vs. Denver Broncos | Noon CT on CBS | Tickets |
| 18 | Saturday / Sunday, Jan. 7 or 8 | @ Las Vegas Raiders | TBD CT on TBD | Tickets |
Betting:
College football odds courtesy of Tipico Sportsbook. Odds updated Saturday at 9:26 AM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
- Spread Favorite: Bills (-2.5)
- Moneyline: Bills (-148), Chiefs (+125)
- Total: 54 points
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